As you can imagine given the aforementioned discussion, there are numerous challenges with respect to the use of EVs for biomarker discovery. The two main components of EVs are RNAs and proteins; we’ll start with the challenges surrounding the former and then move on to those involving the latter. Exosomal RNA is mainly comprised of species between 20-200 nt; including...

The need for a post-isolation clean-up is thus very clear. And that’s exactly why we came up with ExoQuick ULTRA. EVs isolated with ExoQuick ULTRA display a morphology you’d expect with EVs (Image 3.1). Image 3.1: EVs Isolated with ExoQuick ULTRA Display Typical EV Morphology. Taken from powerpoint slide show. Please provide a citation. With ExoQuick ULTRA you’re also able...

We believe that ExoQuick ULTRA is by far the market’s best way of processing individual samples. But what if you need an EV isolation system that’s fast, easy, and high-throughput to boot? What if you need to quickly collect and compare EVs from multiple sources at once? We’ve developed the industry’s leading solution for that, too. It’s called the SmartSEC...

Q. Do EVs secrete nucleocapsids into the bloodstream? A. Given the currently available literature on the point, we know that while nucleocapsids can be found inside of EVs, they aren’t secreting them. Q. What’s the size of the vesicles that you can recover with ExoQuick ULTRA? A. Depending on the prep, between 70-200 nm. Q. What’s the best way to...