Signaling Pathway Reporters

Easily follow signal transduction with our pre-built, ready-to-go vectors that provide qualitative and quantitative data on a variety of signaling pathways

Leveraging SBI’s robust lentivector technology, our pGreenFire signaling pathway reporter vectors accelerate your signal transduction studies with a range of ready-to-transfect, ready-to-package, and ready-to-transduce constructs and pre-built cell lines. Because each pGreenFire construct co-express copGFP and luciferase, you can get both live cell imaging and quantitative pathway activation data from the same cells.

Signaling Pathway Reporters

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pGreenFire Control Pack

Run your pGreenFire projects with confidence with all of the positive and negative pGreenFire1 controls bundled together
Size:10 µg Each (Cat. # TR000PA-1)

pGreenFire1-mCMV Negative Control Lentivector

Run your pGreenFire projects with confidence with the addition of this negative control that drives copGFP and luciferase with a minimal CMV promoter
Sizes:10 µg (Cat. # TR010PA-1), >2 x 10^6 IFUs (Cat. # TR010VA-1)

pGreenFire1-mCMV (EF1α-neo) Negative Control Lentivector

Run your pGreenFire projects with confidence with the addition of this negative control that drives copGFP and luciferase with a minimal CMV promoter (EF1α-neo)
Sizes:10 µg (Cat. # TR010PA-N), >2 x 10^6 IFUs (Cat. # TR010VA-N)

pGreenFire1-mCMV (EF1α-puro) Negative Control Lentivector

Run your pGreenFire projects with confidence with the addition of this negative control that drives copGFP and luciferase with a minimal CMV promoter (EF1α-puro)
Sizes:10 µg (Cat. # TR010PA-P), >2 x 10^6 IFUs (Cat. # TR010VA-P)

pGreenFire1-CMV Positive Control Lentivector

Run your pGreenFire projects with confidence with the addition of this positive control that drives copGFP and luciferase with the strong CMV promoter
Sizes:10 µg (Cat. # TR011PA-1), >2 x 10^6 IFUs (Cat. # TR011VA-1)

pGreenFire1-LXRE-in-CETP Lentivector

Study cholesterol homeostasis by co-expressing dscGFP and luciferase in response to Liver X Receptor (LXR) activity at the CETP promoter
Sizes:2 x 10^6 Cells (Cat. # TR109A-P), 10 µg (Cat. # TR109PA-P), >2 x 10^6 IFUs (Cat. # TR109VA-P)

pGreenFire1-LXRE-in-SREBP1c Lentivector

Study cholesterol homeostasis by co-expressing dscGFP and luciferase in response to Liver X Receptor (LXR) activity at the SREBP1c promoter
Sizes:2 x 10^6 Cells (Cat. # TR100A-P), 10 µg (Cat. # TR100PA-P), >2 x 10^6 IFUs (Cat. # TR100VA-P)

pGreenFire1-PPRE Lentivector

Study cholesterol homeostasis by co-expressing dscGFP and luciferase in response to PPAR activity at the PPAR response element (PPRE)
Sizes:2 x 10^6 Cells (Cat. # TR101A-P), 10 µg (Cat. # TR101PA-P), >2 x 10^6 IFUs (Cat. # TR101VA-P)

pGreenFire1-LXRE-in-LXRα Lentivector

Study cholesterol homeostasis by co-expressing dscGFP and luciferase in response to Liver X Receptor (LXR) activity at the LXRα promoter
Sizes:2 x 10^6 Cells (Cat. # TR102A-P), 10 µg (Cat. # TR102PA-P), >2 x 10^6 IFUs (Cat. # TR102VA-P)

pGreenFire1-LXRE-in-ApoA1 Lentivector

Study cholesterol homeostasis by co-expressing dscGFP and luciferase in response to Liver X Receptor (LXR) activity at the ApoA1 promoter
Sizes:2 x 10^6 Cells (Cat. # TR104A-P), 10 µg (Cat. # TR104PA-P), >2 x 10^6 IFUs (Cat. # TR104VA-P)

pGreenFire1-LXRE-in-Cyp7A1 Lentivector

Study cholesterol homeostasis by co-expressing dscGFP and luciferase in response to Liver X Receptor (LXR) activity at the Cyp7A1 promoter
Sizes:2 x 10^6 Cells (Cat. # TR105A-P), 10 µg (Cat. # TR105PA-P), >2 x 10^6 IFUs (Cat. # TR105VA-P)

pGreenFire1-LXRE-in-ABCA1 Lentivector

Study cholesterol homeostasis by co-expressing dscGFP and luciferase in response to Liver X Receptor (LXR) activity at the ABCA1 promoter
Sizes:2 x 10^6 Cells (Cat. # TR106A-P), 10 µg (Cat. # TR106PA-P), >2 x 10^6 IFUs (Cat. # TR106VA-P)

pGreenFire1-LXRE-in-ABCA1 Lentivector

Study cholesterol homeostasis by co-expressing dscGFP and luciferase in response to Liver X Receptor (LXR) activity at the ABCA1 promoter
Sizes:2 x 10^6 Cells (Cat. # TR107A-P), 10 µg (Cat. # TR107PA-P), >2 x 10^6 IFUs (Cat. # TR107VA-P)

pGreenFire1-LXRE-in-ApoE Lentivector

Study cholesterol homeostasis by co-expressing dscGFP and luciferase in response to Liver X Receptor (LXR) activity at the ApoE promoter
Sizes:2 x 10^6 Cells (Cat. # TR108A-P), 10 µg (Cat. # TR108PA-P), >2 x 10^6 IFUs (Cat. # TR108VA-P)

pGF-p53-mCMV-EF1α-Puro Lentivector

Study oncogenic signaling by co-expressing dscGFP and luciferase in response to p53 activity at p53 transcriptional response elements
Sizes:2 x 10^6 Cells (Cat. # TR200a-p), 10 µg (Cat. # TR200pa-p), >2 x 10^6 IFUs (Cat. # TR200va-p)

pGF-AP1-mCMV-EF1α-Puro Lentivector

Study oncogenic signaling by co-expressing dscGFP and luciferase in response to AP1 activity at AP1 transcriptional response elements
Sizes:2 x 10^6 Cells (Cat. # TR201a-p), 10 µg (Cat. # TR201pa-p), >2 x 10^6 IFUs (Cat. # TR201va-p)

pGF-CREB-mCMV-EF1α-Puro Onco-Response Reporter Lentivector

Study oncogenic signaling by co-expressing dscGFP and luciferase in response to CREB activity at CREB transcriptional response elements
Sizes:2 x 10^6 Cells (Cat. # TR202a-p), 10 µg (Cat. # TR202pa-p), >2 x 10^6 IFUs (Cat. # TR202va-p)

pGF-SMAD2/3/4-mCMV-EF1α-Puro Lentivector

Study oncogenic signaling by co-expressing dscGFP and luciferase in response to SMAD2/3/4 activity at SMAD2/3/4 transcriptional response elements
Sizes:2 x 10^6 Cells (Cat. # TR203a-p), 10 µg (Cat. # TR203pa-p), >2 x 10^6 IFUs (Cat. # TR203va-p)

pGF-EGR1-mCMV-EF1α-Puro Lentivector

Study oncogenic signaling by co-expressing dscGFP and luciferase in response to EGR1 activity at EGR1 transcriptional response elements
Sizes:2 x 10^6 Cells (Cat. # TR204a-p), 10 µg (Cat. # TR204pa-p), >2 x 10^6 IFUs (Cat. # TR204va-p)

pGF-Estrogen Response Element-mCMV-EF1α-Puro Lentivector

Study oncogenic signaling by co-expressing dscGFP and luciferase in response to activity at Estrogen Response Elements
Sizes:10 µg (Cat. # TR205PA-P), >2 x 10^6 IFUs (Cat. # TR205VA-P)