Lentivirus Packaging

Get high-titer, transduction-ready lentivirus backed by expert technical support, flexible production scales, and different titer options

Overview

Get high-titer, transduction-ready virus

High Quality Lentivirus Packaging ServiceWhen it comes to cell line engineering with lentivirus, getting high-quality, high-titer lentivirus preparations is often critical for success, especially with hard-to-transduce cell lines. And when it comes to getting high-quality, high-titer lentivirus, you can reliably turn to the Lentivirus Packaging team at SBI.

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  • Transduction-ready virus
  • Highly experienced team delivers high-quality packaged virus
  • Consistent and reliable titers delivered at or above specified titer levels
  • Three different titer levels and flexible production scales
  • Trusted OEM lentivirus manufacturer for large life science reagent companies
  • Expert technical support, full confidentiality, and on-time delivery with all projects completed on-site in our Palo Alto, CA, facility

Why turn to SBI for lentivirus packaging?

The answer is our experienced service, high-quality packaged virus, and expert support. We've been in the lentiviral packaging business for over a decade—far longer than many companies on the market—and are the trusted OEM partner for lentiviral packaging for several large life science reagent companies. Because all aspects of this service are completed on-site in our Palo Alto, CA, facility, we can offer complete confidentiality, transparency on project status, and fully-informed, expert technical support.

How long does the service take? Is my project too big (or too small)?

Get ready-to-transduce, high-quality, high titer lentiviral preparations at the production scale your project needs—even at large scales of up to 10 mL. Use your own lentivector construct or take advantage of our Syn2Clone or Custom Construct services and we’ll handle vector construction as well. We even have an ultra-high titer offering for demanding applications such as in vivo and stem cell transductions.

Available titer options

Titer IFU/mL Application
Regular Titer >107 Standard cell culture models
High Titer >108 More difficult-to-transduce cells (e.g. suspension cells)
Ultra-high Titer >109 Very difficult-to-transduce cells such as stem cells and primary cells; In vivo applications

If you have any questions about our Lentivirus Packaging Services or don’t see the service you’re looking for, contact us—our scientists are here to help.

How it works

Ordering Lentivirus Packaging Services is easy

Step 1: Contact the services team for a quote by emailing services@systembio.com.

Step 2:  Send us your lentivirus construct and information about the vector, or have us make the vector for you with our Syn2Clone Custom Constructs services.

Step 3: Receive transduction-ready lentivirus

Supporting data

Lentivirus produced by SBI exhibits broad tropism and robust in vivo transduction efficiency

SBI’s Lentivirus Packaging Service Exhibits Broad Tropism

Figure 1. SBI’s packaged lentivirus exhibits broad tropism.

Lentivirus Packaging Service Produced by SBI Delivers High Transduction Efficiency in vivo

Figure 2. Lentivirus produced by SBI delivers high transduction efficiency in vivoDAPI and GFP imaging of mouse liver six days after infection with either no virus (top) or miRZip-33 virus with a GFP marker (bottom). Lentivirus was introduced into mice via retroorbital injection at 2 x 109 IFU/mouse. Rayner, KJ, et al. miR-33 Contributes to the Regulation of Cholesterol Homeostasis. Science. 2010 June 18. 328(5985):1570. Supporting Online Material. PMCID: PMC3114628.