CUSTOM REPORTER CELL LINE GENERATION
Quickly get your studies up and running—have SBI make custom stable cell lines that have GFP, RFP, or luciferase fusions to promoters and enhancer elements.
Get greater insights from in vivo studies with luciferase-labeled cell lines
Why choose SBI’s Stable Cell Line Services?
- Save time by having SBI build your custom cell lines
- Leverage our highly-regarded gene expression and delivery technologies
- Accomplish more with our fast turnaround times and end-to-end services
- Turn to the company that other companies turn to—we are a trusted stable cell line manufacturer for many large pharma/biotech companies
- Enjoy consistent quality, confidentiality, and on-time delivery with all projects completed on-site in our Palo Alto, CA, facility
Available gene expression and delivery technologies
Viral Systems
- Lentivectors—high titer and reliable
- Random integration
- Limited insert size
- High copy number
- Lentivirus Packaging—reliable gene delivery
- High and ultra-high titers
- Efficient transduction
- Optimized reagents
Non-viral Systems
- PhiC31 Integrase System—one-step single-copy integration
- Site-specific integration
- Unlimited insert size
- Single copy number
- PinPoint Targeted Integration System—excellent for creating isogenic cell lines
- Site-specific integration
- Unlimited insert size
- Single copy number
SBI’s Stable Cell Line Services are a great way to leverage our highly-regarded lentivector, PhiC31 Integrase, and PinPoint Targeted Integration technologies.
How it Works
Supporting Data
Successful generation of dual luciferase and GFP-labeled NF-κB cell line
Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI Monitor and quantitatively measure NF-κB transactivation in live cells generated using a dual GFP and luciferase-labeled cell line constructed by SBI Monitor and quantitatively measure NF-κB transactivation in live cells.
Figure 1. Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI—monitor and quantitatively measure NFκB transactivation in live cells. Monitor NF-κB activation in real time with GFP using SBI’s NF-κB/293/GFP-Luc™ Transcriptional Reporter Cell Line (Cat.# TR860A-1).
Figure 2. Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI—monitor and quantitatively measure NFκB transactivation in live cells. Quantitatively measure NF-κB activation in real time with luciferase using SBI’s NF-κB/293/GFP-Luc Transcriptional Reporter Cell Line (Cat.# TR860A-1).
