Custom Luciferase Stable Cell Lines

Reliable, high-quality generation of luciferase-labeled stable cell lines for sensitive in vivo studies

Overview

Get greater insights from in vivo studies with luciferase-labeled cell lines

When you need custom luciferase-labeled cell lines, SBI’s Custom Luciferase-labeled Stable Cell Line Services can save you the time and hassle of making the cell lines yourself. We have access to a range of technologies and an expert team experienced at working with a variety of cell lines, including adherent and suspension cells. The result is hundreds of successfully constructed stable cell lines and highly satisfied customers.

Why choose SBI’s Stable Cell Line Services?

  • Save time by having SBI build your custom cell lines
  • Leverage our highly-regarded gene expression and delivery technologies
  • Accomplish more with our fast turnaround times and end-to-end services
  • Turn to the company that other companies turn to—we are a trusted stable cell line manufacturer for many large pharma/biotech companies
  • Enjoy consistent quality, confidentiality, and on-time delivery with all projects completed on-site in our Palo Alto, CA, facility

Available gene expression and delivery technologies

Viral Systems

  • Lentivectors—high titer and reliable
    • Random integration
    • Limited insert size
    • High copy number
  • Lentivirus Packaging—reliable gene delivery
    • High and ultra-high titers
    • Efficient transduction
    • Optimized reagents

Non-viral Systems

  • PhiC31 Integrase System—one-step single-copy integration
    • Site-specific integration
    • Unlimited insert size
    • Single copy number
  • PinPoint Targeted Integration System—excellent for creating isogenic cell lines
    • Site-specific integration
    • Unlimited insert size
    • Single copy number

Not sure what you need or where to begin? Contact the services team to set up a complimentary phone consultation—email services@systembio.com

How It Works

Ordering Stable Cell Line Services is easy

Step 1. Contact the services team for a quote by emailing services@systembio.com.

Step 2. Send us any necessary materials such as parent cell lines (optional).

Step 3. Receive your stable cell line (turn-around time depends on the complexity of your project).

SBI’s Stable Cell Line Services are a great way to leverage our highly-regarded lentivectorPhiC31 Integrase, and PinPoint Targeted Integration technologies.

Supporting Data

Successful generation of dual luciferase and GFP-labeled NF-κB cell line

Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI Monitor and quantitatively measure NF-κB transactivation in live cells

Figure 1. Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI—monitor and quantitatively measure NFκB transactivation in live cells. Monitor NF-κB activation in real time with GFP using SBI’s NF-κB/293/GFP-Luc™ Transcriptional Reporter Cell Line (Cat.# TR860A-1).

Figure 2. Example of data generated using a dual GFP and luciferase-labeled cell line constructed by SBI—monitor and quantitatively measure NFκB transactivation in live cells. Quantitatively measure NF-κB activation in real time with luciferase using SBI’s NF-κB/293/GFP-Luc Transcriptional Reporter Cell Line (Cat.# TR860A-1).