ExoQuick®-TC UltraPure outperforms both SEC (e.g., qEV) and tangential flow filtration (TFF) in yield and purity for cell culture media applications.

vs. SEC (qEV): Delivers more than 50× higher EV yield, with superior removal of albumin, IgG, and lipoproteins. SEC requires pre-concentration of conditioned media before loading — ExoQuick®-TC UltraPure processes your sample directly, no pre-concentration required.

vs. TFF: At equivalent large-volume inputs (100 mL), EQ-TC UltraPure produces significantly cleaner EV preparations — confirmed by Ponceau S staining and Western blot — with higher EV marker expression and lower protein contamination. Unlike TFF, no specialised tangential flow filtration system is required.