SmartSEC Single provides a higher EV concentration in single fraction than competitors' conventional size exclusion chromatography kits, and it is validated for use with human serum, plasma, and CSF as well as Aplysia californica hemolymph. It is also compatible with most downstream applications, including mass spectrometry, western blotting, nanoparticle tracking analysis (NTA), transmission electron microscopy (TEM), and RNA-sequencing (NGS). No need to choose between yield and purity when one can have both with SmartSEC-Single.