PureFectionTM Transfection Reagent

Deliver more nucleic acids—plasmids, siRNAs, etc.—to cells than the leading lipid-based transfection reagent for effective and reproducible transfection

Description
Size
Catalog Number
Price
Quantity
Add to Cart

PureFection Transfection Reagent

1 mL
LV750A-1
$273

PureFection Transfection Reagent

5 mL
LV750A-5
$1,158

Overview

Increase your transfection efficiencies

With SBI’s PureFectionTM Transfection Reagent, you can deliver more nucleic acid—plasmids, siRNAs, etc.—than the leading lipid-based transfection reagent for effective, efficient, and reproducible transfections.

The easy-to-use protocol consists of a rapid, one-step, 15-minute incubation with the plasmid, small RNA, or other nucleic acid you’d like to transfect. Once the incubation is done, simply add directly to target cells—no media changes are required as PureFection works in the presence of antibiotics and serum.

The fast PureFection protocol makes it well-suited for high-throughput transfection projects.

  • Highly effective transfection technology—works with most cell types
  • Cost-effective alternative to lipid-based products
  • Nanoparticle-based gene delivery with low toxicity
  • Rapid 15-minute protocol makes PureFection ideal for high-throughput transfections
  • Works with both Plasmid DNA and siRNAs

How It Works

A fast and effective method for increasing transfection efficiencies

The PureFection Transfection Reagent uses a fast, 15-minute protocol

Supporting Data

PureFection delivers higher transfection efficiencies than the leading lipid-based reagent

PureFection delivers higher transfection efficiencies than the leading lipid-based reagentPureFection delivers higher transfection efficiencies than the leading lipid-based reagent

Citations

  • Chang, YM, et al. (2017) Alpinia oxyphylla Miq. fruit extract activates IGFR-PI3K/Akt signaling to induce Schwann cell proliferation and sciatic nerve regeneration. BMC Complement Altern Med. 2017 Mar 31; 17(1):184. PM ID: 28359314
  • Chen, YP, et al. (2017) Short-term Hypoxia Reverses Ox-LDL-induced CD36 and GLUT4 Switching Metabolic Pathways in H9c2 Cardiomyoblast Cells. J. Cell. Biochem.. 2017 Apr 4;. PM ID: 28374891
  • Cheng, SY, et al. (2017) Lactate dehydrogenase downregulation mediates the inhibitory effect of diallyl trisulfide on proliferation, metastasis, and invasion in triple-negative breast cancer. Environ. Toxicol.. 2017 Apr 1; 32(4):1390-1398. PM ID: 27566995
  • Liao, PH, et al. (2017) Phosphorylation of cofilin-1 by ERK confers HDAC inhibitor resistance in hepatocellular carcinoma cells via decreased ROS-mediated mitochondria injury. Oncogene. 2017 Apr 6; 36(14):1978-1990. PM ID: 27748761
  • Huang, CY, et al. (2017) Mitochondrial ROS-induced ERK1/2 activation and HSF2-mediated AT1 R upregulation are required for doxorubicin-induced cardiotoxicity.. J. Cell. Physiol.. 2017 Mar 14;. PM ID: 28295305
  • Quan, K, et al. (2017) Icariside II induces cell cycle arrest and apoptosis in human glioblastoma cells through suppressing Akt activation and potentiating FOXO3a activity. Am J Transl Res. 2017 May 31; 9(5):2508-2519. PM ID: 28560001
  • Huang, CY, et al. (2017) HSF1 phosphorylation by ERK/GSK3 suppresses RNF126 to sustain IGF-IIR expression for hypertension-induced cardiomyocyte hypertrophy. J. Cell. Physiol.. 2017 Apr 6;. PM ID: 28383811
  • Chang, WT, Cheng, JT & Chen, ZC. (2016) Telmisartan improves cardiac fibrosis in diabetes through peroxisome proliferator activated receptor δ (PPARδ): from bedside to bench.. Cardiovasc Diabetol. 1970 Jan 1; 15(1):113. PM ID: 27519769
  • Wu, H, et al. (2016) MiR-155 is Involved in Renal Ischemia-Reperfusion Injury via Direct Targeting of FoxO3a and Regulating Renal Tubular Cell Pyroptosis. Cell. Physiol. Biochem.. 2016 Dec 22; 40(6):1692-1705. PM ID: 28006785
  • Hsu, HH, et al. (2016) Taiwanin E inhibits cell migration in human LoVo colon cancer cells by suppressing MMP-2/9 expression via p38 MAPK pathway. Environ. Toxicol.. 2016 Nov 3;. PM ID: 27807932
  • Chuang, TD & Khorram, O. (2016) Tranilast Inhibits Genes Functionally Involved in Cell Proliferation, Fibrosis, and Epigenetic Regulation and Epigenetically Induces miR-29c Expression in Leiomyoma Cells. Reprod Sci. 2016 Jan 1;:1933719116682878. PM ID: 28114878
  • Feng, CC, et al. (2016) Hypoxia suppresses myocardial survival pathway through HIF-1α-IGFBP-3-dependent signaling and enhances cardiomyocyte autophagic and apoptotic effects mainly via FoxO3a-induced BNIP3 expression. Growth Factors. 2016 Aug 1; 34(3-4):73-86. PM ID: 27366871
  • Dotimas, JR, et al. (2016) Diabetes regulates fructose absorption through thioredoxin-interacting protein. Elife. 2016 Oct 11; 5. PM ID: 27725089
  • Shin, JM, et al. (2016) Doxycycline inhibits TGF-β1-induced extracellular matrix production in nasal polyp-derived fibroblasts. Int Forum Allergy Rhinol. 2016 Mar 1; 6(3):256-63. PM ID: 26575862
  • Lin, JC, et al. (2016) β-Catenin overexpression causes an increase in inflammatory cytokines and NF-κB activation in cardiomyocytes.. Cell. Mol. Biol. (Noisy-le-grand). 2016 Jan 30; 63(1):17-22. PM ID: 28234620
  • Huang, CY, et al. (2016) Doxorubicin attenuates CHIP-guarded HSF1 nuclear translocation and protein stability to trigger IGF-IIR-dependent cardiomyocyte death. Cell Death Dis. 2016 Nov 3; 7(11):e2455. PM ID: 27809308
  • Chuang, TD & Khorram, O. (2016) Mechanisms underlying aberrant expression of miR-29c in uterine leiomyoma. Fertil. Steril.. 2016 Jan 1; 105(1):236-45.e1. PM ID: 26453978
  • Fu, CY, et al. (2016) ZAKβ antagonizes and ameliorates the cardiac hypertrophic and apoptotic effects induced by ZAKα. Cell Biochem. Funct.. 2016 Dec 1; 34(8):606-612. PM ID: 27859413
  • Gjymishka, A, et al. (2016) miR-133b Regulation of Connective Tissue Growth Factor: A Novel Mechanism in Liver Pathology. Am. J. Pathol.. 2016 May 1; 186(5):1092-102. PM ID: 26945106
  • Elias, A, et al. (2016) Cancer-specific binary expression system activated in mice by bacteriophage HK022 Integrase. Sci Rep. 2016 Apr 27; 6:24971. PM ID: 27117628