PureFection™ Transfection Reagent
Deliver more nucleic acids—plasmids, siRNAs, etc.—to cells than the leading lipid-based transfection reagent for effective and reproducible transfection
- Highly effective transfection technology—works with most cell types
- Cost-effective alternative to lipid-based products
- Nanoparticle-based gene delivery with low toxicity
- Rapid 15-minute protocol makes PureFection ideal for high-throughput transfections
- Works with both Plasmid DNA and siRNAs
Products
| Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
|---|---|---|---|---|---|---|---|---|
| LV750A-1 | PureFection Transfection Reagent | 1 mL | $303 |
|
||||
| LV750A-5 | PureFection Transfection Reagent | 5 mL | $1287 |
|
||||
Overview
Overview
Increase your transfection efficiencies
With SBI’s PureFection™ Transfection Reagent, you can deliver more nucleic acid—plasmids, siRNAs, etc.—than the leading lipid-based transfection reagent for effective, efficient, and reproducible transfections.
The easy-to-use protocol consists of a rapid, one-step, 15-minute incubation with the plasmid, small RNA, or other nucleic acid you’d like to transfect. Once the incubation is done, simply add directly to target cells—no media changes are required as PureFection works in the presence of antibiotics and serum.
The fast PureFection protocol makes it well-suited for high-throughput transfection projects.
- Highly effective transfection technology—works with most cell types
- Cost-effective alternative to lipid-based products
- Nanoparticle-based gene delivery with low toxicity
- Rapid 15-minute protocol makes PureFection ideal for high-throughput transfections
- Works with both Plasmid DNA and siRNAs
How It Works
How It Works
A fast and effective method for increasing transfection efficiencies
Supporting Data
Supporting Data
PureFection delivers higher transfection efficiencies than the leading lipid-based reagent
FAQs
Resources
Related Products
Citations
-
Tsvetankova, R, et al. (2023) Combined microRNA-141 Rescue and MAPK1 Silencing as Putative Strategy to Support Chemotherapy in Translational Stage towards Metastatic Castration-resistant Prostate Cancer – an In Vitro Model Study. Proceedings of the Bulgarian Academy of Sciences. 2023; 76(8):1286-1296. Link: Proceedings of the Bulgarian Academy of Sciences
-
Wen, SY, et al. (2023) Doxorubicin induced ROS-dependent HIF1α activation mediates blockage of IGF1R survival signaling by IGFBP3 promotes cardiac apoptosis. Aging. 2023; 15(1):164-178. PM ID: 36602546
-
Ichinohe, N, et al. (2023) CINC-2 and miR-199a-5p in exosomes secreted by transplanted Thy1+ cells activate hepatocytic progenitor cell growth in rat liver regeneration. Research Square. 2023;. Link: Research Square
-
Aftab, F, et al. (2023) An intrinsic purine metabolite AICAR blocks lung tumour growth by targeting oncoprotein mucin 1. British journal of cancer. 2023;. PM ID: 36810913
-
Middleton, R, et al. (2023) Newt-derived extracellular vesicles promote mammalian nerve growth. Research Square. 2023;. Link: Research Square
-
Middleton, RC, et al. (2023) Newt A1 cell-derived extracellular vesicles promote mammalian nerve growth. Scientific reports. 2023; 13(1):11829. PM ID: 37481602
-
Wu, H, et al. (2023) Inhibition of microRNA-122 alleviates pyroptosis by targeting dual-specificity phosphatase 4 in myocardial ischemia/reperfusion injury. Heliyon. 2023; 9(7):e18238. Link: Heliyon
-
Mitchell, W, et al. (2023) Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. bioRxiv : the preprint server for biology. 2023;. PM ID: 37425825
-
Kumar, A, et al. (2023) SHP-1 phosphatase acts as a co-activator of PCK1 transcription to control gluconeogenesis. The Journal of biological chemistry. 2023;:105164. PM ID: 37595871
-
Osborne, OM, Kowalczyk, JM & Pierre Louis, KD. (2022) Brain endothelium-derived extracellular vesicles containing amyloid-beta induce mitochondrial alterations in neural progenitor cells. Extracellular Vesicles and Circulating Nucleic Acids. 2022; 3(4):340-361. Link: Extracellular Vesicles and Circulating Nucleic Acids
-
Saggu, S, et al. (2022) Activation of a novel α2AAR-spinophilin-cofilin axis determines the effect of α2 adrenergic drugs on fear memory reconsolidation. Molecular psychiatry. 2022;:1-13. PM ID: 36357671
-
Mai, A, et al. (2022) Thymoquinone induces apoptosis in temozolomide-resistant glioblastoma cells via the p38 mitogen-activated protein kinase signaling pathway. Environmental toxicology. 2022;. PM ID: 36176197
-
Le, Q, et al. (2022) Reversion of glucocorticoid-induced senescence and collagen synthesis decrease by LY294002 is mediated through p38 in skin. International Journal of Biological Sciences. 2022; 18(16):6102-6113. Link: International Journal of Biological Sciences
-
Zhang, WC, et al. (2022) MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state. Cancer gene therapy. 2022;. PM ID: 35840668
-
Stofner, S & Konig, EM. (2022) The role of serine/threonine kinases STK38 and STK38L in human natural killer cells. Thesis. 2022;. Link: Thesis
-
Savill, KMZ, et al. (2022) Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors. Nature communications. 2022; 13(1):2057. PM ID: 35440108
-
Lin, KH, et al. (2021) Diallyl Trisulfide Suppresses High-Glucose-Induced Cardiomyocyte Apoptosis by Targeting Reactive Oxygen Species-Mediated Hypoxia-Inducible Factor-1α/Insulin-like Growth Factor Binding Protein 3 Activation. Journal of agricultural and food chemistry. 2021;. PM ID: 34558885
-
Lin, KH, et al. (2021) MicroRNA-210 repression facilitates advanced glycation end-product (AGE)-induced cardiac mitochondrial dysfunction and apoptosis via JNK activation. Journal of cellular biochemistry. 2021;. PM ID: 34545968
-
Liang, J, et al. (2021) AKR1C3 and Its Transcription Factor HOXB4 Are Promising Diagnostic Biomarkers for Acute Myocardial Infarction. Frontiers in cardiovascular medicine. 2021; 8:694238. PM ID: 34568444
-
Yogeswaran, A, et al. (2021) The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling. Cells. 2021; 10(6). PM ID: 34073556
- See More
PureFection™ Transfection Reagent
$303.00
Products
| Catalog Number | Description | Size | Price | Quantity | Add to Cart | |||
|---|---|---|---|---|---|---|---|---|
| LV750A-1 | PureFection Transfection Reagent | 1 mL | $303 |
|
||||
| LV750A-5 | PureFection Transfection Reagent | 5 mL | $1287 |
|
||||
Overview
Overview
Increase your transfection efficiencies
With SBI’s PureFection™ Transfection Reagent, you can deliver more nucleic acid—plasmids, siRNAs, etc.—than the leading lipid-based transfection reagent for effective, efficient, and reproducible transfections.
The easy-to-use protocol consists of a rapid, one-step, 15-minute incubation with the plasmid, small RNA, or other nucleic acid you’d like to transfect. Once the incubation is done, simply add directly to target cells—no media changes are required as PureFection works in the presence of antibiotics and serum.
The fast PureFection protocol makes it well-suited for high-throughput transfection projects.
- Highly effective transfection technology—works with most cell types
- Cost-effective alternative to lipid-based products
- Nanoparticle-based gene delivery with low toxicity
- Rapid 15-minute protocol makes PureFection ideal for high-throughput transfections
- Works with both Plasmid DNA and siRNAs
How It Works
How It Works
A fast and effective method for increasing transfection efficiencies
Supporting Data
Supporting Data
PureFection delivers higher transfection efficiencies than the leading lipid-based reagent
FAQs
Citations
-
Tsvetankova, R, et al. (2023) Combined microRNA-141 Rescue and MAPK1 Silencing as Putative Strategy to Support Chemotherapy in Translational Stage towards Metastatic Castration-resistant Prostate Cancer – an In Vitro Model Study. Proceedings of the Bulgarian Academy of Sciences. 2023; 76(8):1286-1296. Link: Proceedings of the Bulgarian Academy of Sciences
-
Wen, SY, et al. (2023) Doxorubicin induced ROS-dependent HIF1α activation mediates blockage of IGF1R survival signaling by IGFBP3 promotes cardiac apoptosis. Aging. 2023; 15(1):164-178. PM ID: 36602546
-
Ichinohe, N, et al. (2023) CINC-2 and miR-199a-5p in exosomes secreted by transplanted Thy1+ cells activate hepatocytic progenitor cell growth in rat liver regeneration. Research Square. 2023;. Link: Research Square
-
Aftab, F, et al. (2023) An intrinsic purine metabolite AICAR blocks lung tumour growth by targeting oncoprotein mucin 1. British journal of cancer. 2023;. PM ID: 36810913
-
Middleton, R, et al. (2023) Newt-derived extracellular vesicles promote mammalian nerve growth. Research Square. 2023;. Link: Research Square
-
Middleton, RC, et al. (2023) Newt A1 cell-derived extracellular vesicles promote mammalian nerve growth. Scientific reports. 2023; 13(1):11829. PM ID: 37481602
-
Wu, H, et al. (2023) Inhibition of microRNA-122 alleviates pyroptosis by targeting dual-specificity phosphatase 4 in myocardial ischemia/reperfusion injury. Heliyon. 2023; 9(7):e18238. Link: Heliyon
-
Mitchell, W, et al. (2023) Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. bioRxiv : the preprint server for biology. 2023;. PM ID: 37425825
-
Kumar, A, et al. (2023) SHP-1 phosphatase acts as a co-activator of PCK1 transcription to control gluconeogenesis. The Journal of biological chemistry. 2023;:105164. PM ID: 37595871
-
Osborne, OM, Kowalczyk, JM & Pierre Louis, KD. (2022) Brain endothelium-derived extracellular vesicles containing amyloid-beta induce mitochondrial alterations in neural progenitor cells. Extracellular Vesicles and Circulating Nucleic Acids. 2022; 3(4):340-361. Link: Extracellular Vesicles and Circulating Nucleic Acids
-
Saggu, S, et al. (2022) Activation of a novel α2AAR-spinophilin-cofilin axis determines the effect of α2 adrenergic drugs on fear memory reconsolidation. Molecular psychiatry. 2022;:1-13. PM ID: 36357671
-
Mai, A, et al. (2022) Thymoquinone induces apoptosis in temozolomide-resistant glioblastoma cells via the p38 mitogen-activated protein kinase signaling pathway. Environmental toxicology. 2022;. PM ID: 36176197
-
Le, Q, et al. (2022) Reversion of glucocorticoid-induced senescence and collagen synthesis decrease by LY294002 is mediated through p38 in skin. International Journal of Biological Sciences. 2022; 18(16):6102-6113. Link: International Journal of Biological Sciences
-
Zhang, WC, et al. (2022) MicroRNA-21 guide and passenger strand regulation of adenylosuccinate lyase-mediated purine metabolism promotes transition to an EGFR-TKI-tolerant persister state. Cancer gene therapy. 2022;. PM ID: 35840668
-
Stofner, S & Konig, EM. (2022) The role of serine/threonine kinases STK38 and STK38L in human natural killer cells. Thesis. 2022;. Link: Thesis
-
Savill, KMZ, et al. (2022) Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors. Nature communications. 2022; 13(1):2057. PM ID: 35440108
-
Lin, KH, et al. (2021) Diallyl Trisulfide Suppresses High-Glucose-Induced Cardiomyocyte Apoptosis by Targeting Reactive Oxygen Species-Mediated Hypoxia-Inducible Factor-1α/Insulin-like Growth Factor Binding Protein 3 Activation. Journal of agricultural and food chemistry. 2021;. PM ID: 34558885
-
Lin, KH, et al. (2021) MicroRNA-210 repression facilitates advanced glycation end-product (AGE)-induced cardiac mitochondrial dysfunction and apoptosis via JNK activation. Journal of cellular biochemistry. 2021;. PM ID: 34545968
-
Liang, J, et al. (2021) AKR1C3 and Its Transcription Factor HOXB4 Are Promising Diagnostic Biomarkers for Acute Myocardial Infarction. Frontiers in cardiovascular medicine. 2021; 8:694238. PM ID: 34568444
-
Yogeswaran, A, et al. (2021) The C0-C1f Region of Cardiac Myosin Binding Protein-C Induces Pro-Inflammatory Responses in Fibroblasts via TLR4 Signaling. Cells. 2021; 10(6). PM ID: 34073556
- See More