Thrombin Plasma Prep

De-fibrinate plasma before exosome isolation for efficient recovery and high yields.

Description
Size
Catalog Number
Price
Quantity
Add to Cart

Thrombin Plasma prep for Exosome precipitation (500 µL at 500 U/mL)

Array ( [attributes] => Array ( [attribute_size] => 100 Reactions ) [availability_html] => [backorders_allowed] => [dimensions] => Array ( [length] => [width] => [height] => ) [dimensions_html] => N/A [display_price] => 470 [display_regular_price] => 470 [image] => Array ( [title] => exosome-research-general-01 [caption] => [url] => https://www.systembio.com/wp-content/uploads/exosome-research/exosome-research-general-01.png [alt] => [src] => https://www.systembio.com/wp-content/uploads/exosome-research/exosome-research-general-01.png [srcset] => https://www.systembio.com/wp-content/uploads/exosome-research/exosome-research-general-01.png 345w, https://www.systembio.com/wp-content/uploads/exosome-research/exosome-research-general-01-300x300.png 300w, https://www.systembio.com/wp-content/uploads/exosome-research/exosome-research-general-01-100x100.png 100w [sizes] => (max-width: 345px) 100vw, 345px [full_src] => https://www.systembio.com/wp-content/uploads/exosome-research/exosome-research-general-01.png [full_src_w] => 345 [full_src_h] => 345 [gallery_thumbnail_src] => https://www.systembio.com/wp-content/uploads/exosome-research/exosome-research-general-01-100x100.png [gallery_thumbnail_src_w] => 100 [gallery_thumbnail_src_h] => 100 [thumb_src] => https://www.systembio.com/wp-content/uploads/exosome-research/exosome-research-general-01-300x300.png [thumb_src_w] => 300 [thumb_src_h] => 300 [src_w] => 345 [src_h] => 345 ) [image_id] => 7579 [is_downloadable] => [is_in_stock] => 1 [is_purchasable] => 1 [is_sold_individually] => no [is_virtual] => [max_qty] => [min_qty] => 1 [price_html] => $470 [sku] => TMEXO-1 [variation_description] =>

Thrombin Plasma prep for Exosome precipitation (500 µL at 500 U/mL)

[variation_id] => 65675 [variation_is_active] => 1 [variation_is_visible] => 1 [weight] => [weight_html] => N/A )
100 Reactions
TMEXO-1
$ 470
Contact Us Speak to a specialist
1-888-266-5066

Overview

Efficient exosome isolation from plasma
“We therefore pursued the ExoQuick® method for further study, as these samples required much less sample input, a key benefit when working with clinical samples and mouse models1.”
 
When isolating exosomes from plasma, fibrinogen and fibrin can impede efficient recovery. By pre-treating plasma with thrombin, the fibrinogen can be converted to fibrin and easily pre-cleared by a simple centrifugation step. The resulting serum-like solution can now be treated with ExoQuick, original formulation, for quantitative exosome isolation that is compatible with high-throughput methods.

Want to learn more about how ExoQuick works? Find out here.

Choose the right ExoQuick for your application:

Application Product Catalog #
Purest EV isolation ExoQuick ULTRA and
ExoQuick-TC ULTRA
EQULTRA-20A-1
EQULTRA-20TC-1
General purpose EV isolation ExoQuick and
ExoQuick-TC
EXOQ20A-1
EXOTC50A-1
EV isolation for pre-clinical/in vivo studies ExoQuick-CG EXOCG50A-1
EV isolation that removes contaminating lipoprotein particles from plasma or serum ExoQuick-LP EXOLP5A-1
EV isolation that includes a de-fibrinating plasma step prior to isolation ExoQuick Plasma Prep with Thrombin EXOQ5TM-1


REFERENCES

  1. Chugh PE, et al. Systemically Circulating Viral and Tumor-Derived MicroRNAs in KSHV-Associated Malignancies. PLoS Pathog. 2013. 9(7): e1003484. PMCID: PMC3715412.