NanoEX™ Automated Bio-nanoparticle Isolation Platform
From discovery to scale: transform EV isolation with NanoEX™.
Push EV Isolation Beyond Bench Scale
System Biosciences (SBI) is excited to introduce the NanoEX™ Automated Bio-nanoparticle Isolation Platform, powered by VanoFlow® Patented Asymmetric Nanopore Membrane (ANM) Technology.
Unlike conventional ultrafiltration membranes that clog, trap proteins, and shear vesicles, NanoEX’s ANM offers:
- Highly uniform pore size (<10% CV) for reproducible results.
- Cone-shaped channels that eliminate clogging and improve flow.
- Gentle processing that minimizes EV loss and protein aggregation while preserving biomarker integrity.

With NanoEX, SBI has the power to extend its trusted small-volume kits (10 μL – 50 mL) into the liter-scale arena, enabling seamless transition from bench research to clinical and manufacturing applications.
Performance Highlights
Unparalleled yield & purity
Highest recovery with clean EV fractions.
Ease of use
Hands-on time under 5 minutes; guided touchscreen workflow; single-use cassettes.
Scalable throughput
Process 20 mL to >1 L in hours, not days.
Automation you can trust
Fully enclosed, fully automated runs for consistent results.
Where NanoEX Makes the Difference
Therapeutic pipeline
Intact vesicles for translational & clinical workflows.
Biomanufacturing scale-up
Consistent lots for preclinical/commercial scale.
Biomarker discovery
High-purity EVs for omics & diagnostics.
Regenerative & cosmetic
Liter-scale output when you need it.
Start Small → Scale
1Start small — Validate with SBI kits.
2Scale seamlessly — Transition to NanoEX for liter-scale processing.
3Stay supported — One partner from benchtop to biomanufacturing.

Key Specifications
- Uniform pore size (<10% CV)
- Automated, enclosed workflow
- Throughput: 20 mL → >1 L
- Single-use cassettes
- Touchscreen operation
Why Partner with SBI
With over a decade of EV innovation and 70% of our portfolio built on extracellular vesicles, SBI delivers solutions that evolve with the field. NanoEX establishes SBI not just as a kit provider, but as a full-spectrum EV technology leader.
- End-to-end EV portfolio
- Bench to biomanufacturing support
- Global customer success