NanoEX™ Automated Bio-nanoparticle Isolation Platform

From discovery to scale: transform EV isolation with NanoEX™.

Push EV Isolation Beyond Bench Scale

System Biosciences (SBI) is excited to introduce the NanoEX™ Automated Bio-nanoparticle Isolation Platform, powered by VanoFlow® Patented Asymmetric Nanopore Membrane (ANM) Technology.

Unlike conventional ultrafiltration membranes that clog, trap proteins, and shear vesicles, NanoEX’s ANM offers:

  • Highly uniform pore size (<10% CV) for reproducible results.
  • Cone-shaped channels that eliminate clogging and improve flow.
  • Gentle processing that minimizes EV loss and protein aggregation while preserving biomarker integrity.

With NanoEX, SBI has the power to extend its trusted small-volume kits (10 μL – 50 mL) into the liter-scale arena, enabling seamless transition from bench research to clinical and manufacturing applications.

Performance Highlights

Unparalleled yield & purity

Highest recovery with clean EV fractions.

Ease of use

Hands-on time under 5 minutes; guided touchscreen workflow; single-use cassettes.

Scalable throughput

Process 20 mL to >1 L in hours, not days.

Automation you can trust

Fully enclosed, fully automated runs for consistent results.

Where NanoEX Makes the Difference

Therapeutic pipeline

Intact vesicles for translational & clinical workflows.

Biomanufacturing scale-up

Consistent lots for preclinical/commercial scale.

Biomarker discovery

High-purity EVs for omics & diagnostics.

Regenerative & cosmetic

Liter-scale output when you need it.

Start Small → Scale

1Start small — Validate with SBI kits.

2Scale seamlessly — Transition to NanoEX for liter-scale processing.

3Stay supported — One partner from benchtop to biomanufacturing.

Key Specifications

  • Uniform pore size (<10% CV)
  • Automated, enclosed workflow
  • Throughput: 20 mL → >1 L
  • Single-use cassettes
  • Touchscreen operation

Why Partner with SBI

With over a decade of EV innovation and 70% of our portfolio built on extracellular vesicles, SBI delivers solutions that evolve with the field. NanoEX establishes SBI not just as a kit provider, but as a full-spectrum EV technology leader.

  • End-to-end EV portfolio
  • Bench to biomanufacturing support
  • Global customer success