Elevate sEV Purity with SmartSEC-DeLipo™ for Flawless Isolation

Conventional size exclusion chromatography (SEC) is commonly used for isolating high-purity extracellular vesicles (EVs). However, relying solely on size can lead to lipoprotein contamination, which may skew biomarker analysis and obscure EV effects. To improve the functional analysis of circulating EVs in blood, it’s essential to remove lipoproteins.

Our SmartSEC-DeLipo Kit offers superior purity and yield by effectively depleting lipoproteins, such as HDL, LDL, VLDL, and chylomicrons during sEV isolation. This advanced kit consistently produces high yields of pure sEVs, free from lipoprotein interference -- making it ideal for downstream applications like RNA sequencing, proteomics, and functional studies. By selectively removing lipoproteins, like ApoB and ApoE, the SmartSEC-DeLipo Kit ensures the isolation of pure sEV populations, setting a new standard for purity.