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      • Exosome Research
          • Exosome Isolation

            • Start your exosome research right with products that simplify high-quality exosome isolation

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          • Exosome Detection

            • Easily detect the presence of exosomes with general and tissue-specific antibodies and arrays, as well as reagents that label exosomes

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          • Exosome Quantitation

            • When you need to know the amount of exosomes you’ve isolated, SBI offers a range of options that meet most quantitation needs

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          • Exosome Labeling

            •  Easily track exosomes and their cargo with our ready-to-go Cyto-Tracers, ExoGlow reagents, and XPACK products, as well as make-your-own XPACK lentivectors

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          • Biomarker Profiling

            • Whether you’re interested in characterizing exosomal RNA or proteins for biomarker profiling, SBI offers a range of intuitive, easy-to-use products

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          • Exosome Engineering

            • When you’re ready to move from simply studying exosomes to using them as research tools, SBI offers a complete set of products for exosome engineering

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      • CRISPR/Cas9 Systems
          • Cas9 & gRNA Delivery

            • Find the best Cas9 and gRNA delivery options for your genome engineering application—choose from mRNA, lentivectors, protein, AAV, and more

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          • Multiplex gRNA Cloning

            • Increase the efficiency of making multiple changes to a genome with our Multiplex gRNA Cloning Products

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          • Cas9 Detection

            • Move your genome engineering projects forward with confidence with products for verifying Cas9 mRNA and protein expression

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          • HR Targeting Vectors

            • Whether you’re using CRISPR/Cas9 for gene knock-ins, knock-outs, or edits, SBI’s ready-to-clone HR Targeting Vectors are carefully designed for easier workflows

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          • AAVS1 Safe Harbor Targeting

            • Leverage the power of the AAVS1 Safe Harbor Site for robust gene expression with these HR donor vectors already targeted to the AAVS1 site

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          • EZ-Genotyping Kit

            • Fast, streamlined genotyping of cultured mammalian cells using a protocol that mitigates the risk of sample cross-contamination

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          • CLOuD9 Gene Expression Regulation System

            • Explore a new frontier in the study of gene expression regulation with inducible, reversible chromatin loop formation at your location-of-interest

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      • Lentivirus Production
          • LentiSuite & LentiStarter Kits

            • New to lentivirus or scaling up production? Our LentiSuite and LentiStarter Kits provide all of SBI’s great lentivirus products in ready-to-go kits

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          • Virus Packaging

            • Get high-quality, high-titer lentivirus with our well-regarded lentivirus packaging systems, available in both integrating and non-integrating systems

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          • Virus Concentration & Titering

            • Find what you need for fast lentivirus titering as well as lentivirus concentration

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          • Transduction & Transfection

            • Improve transduction and transfection efficiencies with high-quality reagents that really deliver

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          • Pre-packaged Control Viruses

            • Get the confidence of controls and move forward fast with SBI’s ready-to-transduce, pre-packaged control viruses—in a range of marker and promoter options

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      • Gene Expression Systems
          • Lentiviral Vectors

            • Get reliable, stable gene expression from SBI’s highly-regarded lentivectors—our wide range of promoters and reporters support a wealth of applications

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          • AAV Expression

            • Get the efficiency of transduction without viral integration with our AAV-based expression systems—great for gene therapy research and more

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          • Cumate-inducible Systems

            • For the ultimate in gene expression control, use SBI’s cumate-inducible systems—up to 32-fold induction that’s titratable, reversible, and background-free

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          • PiggyBac Transposon

            • Easy, consistent transgenesis free from limitations on insert size and available in a footprint-free format

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          • Integrase-based Systems

            • When you want non-viral expression from low or single-copy integration events, and/or have a large insert size, choose one of SBI’s integrase-based systems

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          • Minicircle Technology

            • Get sustained, episomal gene expression free from foreign DNA—great for model animal generation and gene therapy research

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          • EEV Systems

            • An easy-to-produce non-integrating option for gene expression that can deliver sustained expression from a non-viral system

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          • mRNA Synthesis

            • From an efficient system for in vitro transcription to ready-to-transfect pre-made mRNA transcripts, SBI streamlines your mRNA production

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          • Cold Fusion Cloning

            • The Cold Fusion technology is a simple, rapid and highly efficient cloning kit

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          • T Cell Research Tools

            • Simplify your studies of T cell dynamics with SBI’s ready-to-use, pre-built Treg and Th17 vectors and cell lines

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          • CLOuD9 Gene Expression Regulation System
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      • Imaging & Reporter Vectors
          • Signaling Pathway Reporters

            • Easily follow signal transduction with our pre-built, ready-to-go vectors that provide qualitative and quantitative data on a variety of signaling pathways

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          • Bioluminescent Imaging Vectors

            • Clearly visualize cells in vivo and ex vivo for tracking cell fate and more with our pre-built imaging vectors

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          • Cyto-Tracers

            • Jumpstart your studies of dynamic cellular processes and subcellular localization with our pre-built Cyto-Tracer Vectors

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          • Stem Cell Reporters

            • Save time with our ready-to-go pGreenFire, pGreenZeo, pRedZeo, and pRedTK vectors for monitoring pluripotency and tracking differentiation

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          • T Cell Research Tools

            • Simplify your studies of T cell dynamics with SBI’s ready-to-use, pre-built Treg and Th17 vectors and cell lines

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      • miRNA & lncRNA Research Tools
          • Lenti-miR Precursor Vectors

            • Alter gene expression or study miR function with human and mouse lentivector-delivered precursors that are efficiently and accurately processed into mature miRs

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          • Lenti-miR Libraries

            • Leverage SBI’s powerful and highly-effective Lenti-miR technology for efficient miRNA screening with our pooled Lenti-miR libraries

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          • miRZip Knockdown Vectors

            • Permanently knockdown miRs with SBI’s miRZip anti-miRNA Expression Lentivectors

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          • miRNA qPCR Profiling

            • Quickly and easily obtain highly accurate qPCR profiling of miRNAs with sample prep kits and ready-to-use arrays

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          • LncRNA qPCR Profiling

            • Quickly and easily obtain highly accurate qPCR profiling of lncRNAs with sample prep kits and ready-to-use arrays

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  • Applications
      • Biomarker Discovery
      • Cancer Research
      • CAR-T Research
      • Exosome Isolation
      • Exosome Characterization
      • Exosome Engineering
      • Gene Delivery
      • Gene Editing
      • Gene Knock-ins & Knock-outs
      • Inducible Gene Expression
      • In Vivo Imaging
      • iPSC Generation
      • Stem Cell Lineage Tracking
      • Lentiviral Production
      • Molecular Cloning
      • Noncoding RNA Research
      • qPCR-based Expression Profiling
      • Signal Transduction

      • Find the SBI product or service that supports your specific research application

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  • Services
        • Exosome Services
            • Exo-NGS
            • Exosome Proteomics Services
            • Exosome Lipidomics & Metabolomics Services
            • NTA-based Exosome Characterization
            • Exosome Isolation & Manufacturing
            • Exosome Engineering
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        • CRISPR/Cas9 Services
            • CRISPR/Cas9 gRNA and HR Donor Cloning
            • CRISPR/Cas9 Cell Line Engineering
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        • Syn2Clone Custom Constructs
        • Lentivirus Packaging
        • Stable Cell Lines
            • Custom Overexpression Stable Cell Lines
            • Custom Luciferase-labeled Stable Cell Lines
            • Reporter Cell Lines
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        • Minicircle Services
        • RNA Services
            • mRNA Synthesis Services
            • miRNA & lncRNA Profiling Services
            • Custom miRNA Precursor and anti-miRNA (miRZip) Services
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      • SBI can streamline your research with an array of custom services to suit your needs

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  • Resources
      • Webinars & Videos
      • Documentation
      • SBI Products in the Literature
      • Classes
      • Request a Free Sample

      • Get in-depth information about SBI’s products and services with videos, webinars, product manuals, and more

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  • Blog
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      • Our Mission
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      • Contact Us

      • Learn more about System Biosciences, plus upcoming events, intellectual property, and careers

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Studying Biomarkers?

SBI offers products and services that simplify biomarker discovery from exosomes. Whether you’re looking at exosomal protein, miRNA, lipids, or metabolites, our services are end-to-end and our products are backed by expert scientific support.

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