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Direct Reprogramming Factors

Expression vectors to directly convert one cell type to another

Reprogram cellular identities

  • Collection of transcription factors and microRNAs
  • Explore novel conversion cocktails
  • Make patient-specific cells and tissues

Direct Reprogramming Factors

Transdifferentiation (TD) is the direct conversion of one cell type to another. This reprogramming method provides a fast route for creating novel cell types and manufacturing functional tissues. TD enables the generation of patient-specific cell types without the risk of creating potentially tumorigenic induced pluripotent stem cells before differentiation. The TD-Consortium, offered by SBI, includes collections of transcription factors and microRNA precursors built in constitutive or inducible vector formats to allow you to harness the TD technology and advance regenerative medicine research.

Recent History of Transdifferentiation