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Pathway Focused

Dissect specific signaling pathways

Discover new targets in druggable pathways

  • Kinase
  • Phosphatase
  • Apoptosis

Pathway focused shRNA libraries

GeneNet™ Focused shRNA Libraries encode a pooled set of shRNAs designed against all genes of a specific function or class, enabling targeted high-throughput RNAi screens. The focused shRNA libraries are constructed using a lentiviral delivery system so they may be introduced into almost any cell type.

SBI is pleased to offer the following Focused shRNA Libraries targeting a
comprehensive list of Human genes for each class:

Each Focused shRNA Library offes the following Features and Benefits:

  • Selectable puromycin resistance allows positive identification and selection of transduced cells
  • Pre-packaged, ready-to-use format—transduce your cells the day you receive the library
  • High-throughput identification of functional siRNAs by Affymetrix GeneChip® hybridization
  • High-quality, high-titer viral delivery using HIV-based lentivectors
  • Also available in plasmid form, you can now produce large quantities of packaged siRNA library in your own lab