Cas9 & gRNA Delivery

Find the best Cas9 and gRNA delivery options for your genome engineering application—choose from mRNA, lentivectors, protein, AAV, and more

With a wealth of options for delivering Cas9 and gRNA, SBI supports a full range of genome engineering applications. Deliver Cas9 and gRNA via mRNA, lentivector, or AAV, or use purified Cas9 protein, and then choose from our all-in-one systems that deliver Cas9 and gRNA on a single vector or two-component systems for separate introduction of Cas9 and gRNA.

Not sure which system to choose? Take a look at our table below, or contact technical support—we’re here to help you find the right product for your application and can provide expert experimental support.

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Cas9 SmartNickaseTM mRNA, Injection- and Transfection-ready

Use injection- and transfection-ready Cas9 SmartNickase mRNA for in vivo genome editing projects where you need to limit off-target activity
Size:20 µg (Cat. # CAS504A-1)

hspCas9-T2A-GFP SmartNucleaseTM mRNA, Injection- and Transfection-ready

When you want to be sure - verify that your Cas9 mRNA has been successfully transfected into target cells with Cas9 SmartNuclease mRNA that also delivers GFP
Size:10 µg (Cat. # CAS530G-1)

hspCas9-T2A-RFP SmartNucleaseTM mRNA, Injection- and Transfection-ready

When you want to be sure - verify that your Cas9 mRNA has been successfully transfected into target cells with a Cas9 SmartNuclease mRNA that also delivers RFP
Size:10 µg (Cat. # CAS531R-1)

hspCas9-T2A-GFP SmartNickaseTM mRNA, Transfection-ready

When you want to be sure—verify that your Cas9 SmartNickase mRNA has been successfully transfected into target cells with an mRNA that also delivers GFP
Size:10 µg (Cat. # CAS534G-1)

hspCas9-T2A-RFP SmartNickaseTM mRNA, Transfection-ready

When you want to be sure—verify that your Cas9 SmartNickase mRNA has been successfully transfected into target cells with an mRNA that also delivers RFP
Size:10 µg (Cat. # CAS535R-1)

Cas9 SmartNucleaseTM mRNA, Injection- and Transfection-ready

Move in vivo genome editing projects forward faster with injection- and transfection-ready Cas9 SmartNuclease mRNA
Sizes:20 µg (Cat. # CAS500A-1), 20 µg (Cat. # CAS502A-1)

Cas9 SmartNucleaseTM AAVS1 gRNA, Transfection-ready

Easily target Cas9 activity to the AAVS1 Safe Harbor Site with this pre-built gRNA specific for AAVS1
Size:10 µg (Cat. # CAS520A-1)