All CRISPR/Cas9 Products

Pairing flexibility and choice with experienced scientific support, our wide range of CRISPR/Cas9 products put the power of genome engineering into your hands

Ready to use CRISPR/Cas9? Then SBI’s ready for you. With a comprehensive selection of CRISPR/Cas9 products for genome engineering—including Cas9 and gRNA delivery systems in a flexible range of formats, homologous recombination donor vectors, and AAVS1 Safe Harbor targeting—we can bring your genome engineering projects to life. Even better, our experienced technical support team is available to answer your questions on vector design, experimental setup, and more—just use the Contact page to start the conversation.

All CRISPR/Cas9 Products


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All CRISPR/Cas9 Products

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PiranhaTM Targeted Protein Degradation
HEK293T GFP/Puromycin Stable Cell Line

Ready-to-go cell line for targeted protein degradation screens—just add antibodies—the Piranha system is constitutively expressed in HEK293T cells.
Size:>1x10^6 cell/vial (Cat. # PTPD600A-1)

pCDH-CMV-Piranha-EF1-GFP-T2A-Puro Pre-packaged Lentivirus

Create your own targeted protein degradation cell line using SBI’s exclusive ready-to-transduce Piranha lentivirus marked with GFP and puromycin.
Size:>1 x 10^6 IFUs (Cat. # PTPD513VA-1)

pCDH-EF1a-Piranha-T2A-Puro Pre-packaged Lentivirus

Use ready-to-transduce Piranha lentivirus marked with puro and expressed from the EF1α promoter to build your own targeted protein degradation cell line.
Size:>1 x 10^6 IFUs (Cat. # PTPD527VA-1)

CAG-T7-hspCas9-T2A-RFP-H1-gRNA All-in-one Cas9 SmartNucleaseTM Plasmid

Easily verify transfection efficiencies with this All-in-one Cas9 SmartNuclease Plasmid that coordinately expresses RFP-CAG-T7-hspCas9-T2A-RFP-H1-gRNA
Size:10 Reactions (Cat. # CAS721R-1)

CMV-T7-hspCas9-Nickase-T2A-RFP-H1-gRNA All-in-one Cas9 SmartNickaseTM Plasmid

Easily verify transfection efficiencies with this All-in-one Cas9 SmartNickase Plasmid that coordinately expresses RFP-CMV-T7-hspCas9-Nickase-T2A-RFP-H1-gRNA
Size:10 Reactions (Cat. # CAS791R-1)

EF1α-RFP-U6-gRNA(SA) Two Vector AAV Cas9 SmartNucleaseTM gRNA Expression Plasmid

Extend genome editing capabilities to cutting edge in vivo applications with our Two Vector AAV Cas9 SmartNuclease gRNA Expression Plasmid EF1α-RFP-U6-gRNA(SA).
Size:10 Reactions (Cat. # CASAAV300PA-1)

EF1α-Blasticidin-U6-gRNA Two Vector Cas9 SmartNucleaseTM gRNA Expression Lentivector

Efficient lentivector delivery of gRNA for our Two Vector Cas9 SmartNuclease System - EF1α-Blasticidin-U6-gRNA.
Size:10 Reactions (Cat. # CASLV510PA-B)

CMV-T7-hspCas9-H1-gRNA All-in-one Cas9 SmartNucleaseTM Plasmid

Clone your own gRNA into this vector and simplify delivery of hspCas9 and gRNA.
Size:10 Reactions (Cat. # CAS740A-1)

EF1α-hspCas9-nickase-H1-gRNA All-in-one Cas9 SmartNickase Plasmid (circular)

Use this first-generation SBI EF1α-hspCas9 SmartNickase when you want to reduce off-target events, have transfectable cells, and prefer an intact vector.
Size:10 µg (Cat. # CAS800A-1)

CMV-hspCas9-T2A-Puro Two Vector Cas9 SmartNucleaseTM Lentivector

When working with difficult-to-transfect-cells, use our lentiviral Cas9 SmartNuclease System. This vector drives Cas9 expression with CMV and has Puro selection.
Sizes:10 µg (Cat. # CASLV100PA-1), 1 Kit (Cat. # CASLV100PA-KIT), 2 x 25 µL (Cat. # CASLV100VA-1)

EF1α-GFP-U6-gRNA Two Vector Cas9 SmartNucleaseTM gRNA Expression Lentivector

Efficient lentivector delivery of gRNA for our Two Vector Cas9 SmartNuclease System—EF1α-GFP-U6-gRNA.
Size:10 Reactions (Cat. # CASLV511PA-G)

CMV-T7-hspCas9-H1-gRNA All-in-one Cas9 SmartNucleaseTM Plasmid & Multiplex gRNA Cloning Kit

Easily create an All-in-one Cas9 SmartNuclease Plasmid that delivers multiple gRNAs—kit bundles CMV-T7-hspCas9-H1-gRNA with the Multiplex gRNA Cloning Kit
Size:10 Reactions (Cat. # CAS740A-KIT)

EF1α-hspCas9-DM-H1-gRNA All-in-one Cas9 Null Nuclease Plasmid (circular)

Use the EF1α-hspCas9-DM-H1-gRNA All-in-one Cas9 Null Nuclease Plasmid as a DNA cleavage/DNA nicking-deficient control for your studies.
Size:10 µg (Cat. # CAS805A-1)

CMV-hspCas9-EF1α-GFP Two Vector Cas9 SmartNucleaseTM Lentivector

When working with difficult-to-transfect-cells, use our lentiviral Cas9 SmartNuclease System. This vector drives Cas9 expression with CMV and has a GFP marker.
Sizes:10 µg (Cat. # CASLV105PA-1), 1 Kit (Cat. # CASLV105PA-KIT), 2 x 25 µL (Cat. # CASLV105VA-1)

EF1α-RFP-U6-gRNA Two Vector Cas9 SmartNucleaseTM gRNA Expression Lentivector

Efficient lentivector delivery of gRNA for our Two Vector Cas9 SmartNuclease System—EF1α-RFP-U6-gRNA.
Size:10 Reactions (Cat. # CASLV512PA-R)

CMV-T7-hspCas9-T2A-GFP-H1-gRNA All-in-one Cas9 SmartNucleaseTM Plasmid

Easily verify transfection efficiencies with this All-in-one Cas9 SmartNuclease Plasmid that coordinately expresses GFP- CMV-T7-hspCas9-T2A-GFP-H1-gRNA
Size:10 Reactions (Cat. # CAS740G-1)

CAG-hspCas9-nickase-H1-gRNA All-in-one Cas9 SmartNickase Plasmid (circular)

Use this first-generation SBI CAG-hspCas9 SmartNickase when you want to reduce off-target events, have transfectable cells, and prefer an intact vector.
Size:10 µg (Cat. # CAS820A-1)

MSCV-hspCas9-T2A-Puro Two Vector Cas9 SmartNucleaseTM Lentivector

When working with difficult-to-transfect-cells, use our lentiviral Cas9 SmartNuclease System. This vector drives Cas9 expression with MSCV and has Puro selection.
Sizes:10 µg (Cat. # CASLV120PA-1), 1 Kit (Cat. # CASLV120PA-KIT), 2 x 25 µL (Cat. # CASLV120VA-1)

CMV-hspCas9-T2A-Puro-H1-AAVS1_gRNA All-in-one Cas9 SmartNucleaseTM & AAVS1 gRNA Lentivector

Streamline genome editing at the AAVS1 Safe Harbor Site in hard-to-transfect cells with a lentivector that expresses both Cas9 and an AAVS1-targeting gRNA
Sizes:10 µg (Cat. # CASLV601PA-1), 2 x 25 µL (Cat. # CASLV601VA-1)

CMV-T7-hspCas9-T2A-RFP-H1-gRNA All-in-one Cas9 SmartNucleaseTM Plasmid

Easily verify transfection efficiencies with this All-in-one Cas9 SmartNuclease Plasmid that coordinately expresses RFP-CMV-T7-hspCas9-T2A-RFP-H1-gRNA
Size:10 Reactions (Cat. # CAS741R-1)

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