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miRZips anti-microRNAs

Permanent microRNA suppression

Permanent microRNA interference

  • Lentiviral-based anti-sense microRNAs
  • Use both GFP and Puro selection
  • Dissect microRNA regulated pathways

miRZips™ Lentiviral-based MicroRNA Inhibition

Features and Benefits

  • Stable & permanent anti-microRNA expression from constitutive H1 promoter
  • Rationally designed, asymmetric hairpins optimized for anti-sense microRNA production
  • miRZip anti-sense microRNAs efficiently suppress specific endogenous microRNAs
  • Reliable delivery to dividing or non-dividing cells
  • Select for positive expressing cells with either GFP or Puro selection
  • Uncover phenotypes using powerful anti-microRNA interference
  • Pool of prepackaged viral particles containing the entire anti-microRNA collection for high-throughput phenotypic screens also available

• List of miRZip clones