miR and PIWI-SNaREs™
Immunopurify microRNA and piRNA complexes
and their associated RNAs
HA-tagged microRNA and piRNA factors
- DGCR8 (Pasha)
- DICER
- Argonautes 1, 2, 3, 4
- Human PIWI factors
Online Resources
Product Citations
Uchino K, Takeshita F, Takahashi RU, Kosaka N, Fujiwara K, Naruoka H, Sonoke S, Yano J, Sasaki H, Nozawa S, Yoshiike M, Kitajima K, Chikaraishi T, Ochiya T. Therapeutic effects of microRNA-582-5p and -3p on the inhibition of bladder cancer progression. Mol Ther. 2013 Mar;21(3):610-9.
Technical References
MicroRNA-binding Protein Factors
Hendrickson DG, Hogan DJ, Herschlag D, Ferrell JE, Brown PO (2008) Systematic Identification of mRNAs Recruited to Argonaute 2 by Specific microRNAs and Corresponding Changes in Transcript Abundance. PLoS ONE 3(5): e2126 (PDF). »
Fedor V. Karginov, Cecilia Conaco, Zhenyu Xuan, Bryan H. Schmidt, Joel S. Parker, Gail Mandel, and Gregory J. Hannon. Proc Natl Acad Sci U S A. 2007 December 4; 104(49): 19291–19296. A biochemical approach to identifying microRNA targets.
Goff LA, Davila J, Swerdel MR, Moore JC, Cohen RI, Wu H, Sun YE, Hart RP. Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors. PLoS One. 2009 Sep 28;4(9):e7192. (PDF). »
Persson H, Kvist A, Vallon-Christersson J, Medstrand P, Borg A, Rovira C. Nat Cell Biol. 2009 Oct;11(10):1268-71. The non-coding RNA of the multidrug resistance-linked vault particle encodes multiple regulatory small RNAs.
G. Meister, M. Landthaler, L. Peters, P. Chen, H. Urlaub, R. Lührmann, T. Tuschl. Current Biology, Volume 15, Issue 23, Pages 2149–2155. Identification of Novel Argonaute-Associated Proteins.
Elisavet Maniataki and Zissimos Mourelatos. RNA. 2005 June; 11(6): 849–852. Human mitochondrial tRNAMet is exported to the cytoplasm and associates with the Argonaute 2 protein.
Savas JN, Makusky A, Ottosen S, Baillat D, Then F, Krainc D, Shiekhattar R, Markey SP, Tanese N. Proc Natl Acad Sci U S A. 2008 Aug 5;105(31):10820-5. Huntington's disease protein contributes to RNA-mediated gene silencing through association with Argonaute and P bodies.
PIWI Protein Factors
Hang Yin & Haifan Lin. An epigenetic activation role of Piwi and a Piwi-associated piRNA in Drosophila melanogaster. Nature 450, 304-308 (8 November 2007).
Carla Klattenhoff and William Theurkau. Biogenesis and germline functions of piRNAs. Development 135, 3-9 (2008).



