Exo-Fect™ Exosome Transfection
Transfer RNA and DNA into exosomes
Simple, fast protocol
- No electroporation required
- Load siRNA and microRNA
- Works with mRNA as well
- Transfer plasmid DNA into exosomes
- Insert small molecule drugs into exosomes
Online Resources
Technical References and Product Citations
Peterson MF, Otoc N, Sethi JK, Gupta A, Antes TJ. Integrated systems for exosome investigation. Methods. 2015 Apr 24. pii: S1046-2023(15)00161-9.
Marcus ME, Leonard JN. FedExosomes: Engineering Therapeutic Biological Nanoparticles that Truly Deliver. Pharmaceuticals (Basel). 2013;6(5):659-80.
Zomer A, Vendrig T, Hopmans ES, van Eijndhoven M, Middeldorp JM, Pegtel DM. Exosomes: Fit to deliver small RNA. Commun Integr Biol. 2010 Sep;3(5):447-50.
Pegtel DM, Cosmopoulos K, Thorley-Lawson DA, van Eijndhoven MA, Hopmans ES, Lindenberg JL, de Gruijl TD, Wurdinger T, Middeldorp JM. Functional delivery of viral miRNAs via exosomes. Proc Natl Acad Sci U S A. 2010 Apr 6;107(14):6328-33.
Momen-Heravi F, Bala S, Bukong T, Szabo G. Exosome-mediated delivery of functionally active miRNA-155 inhibitor to macrophages. Nanomedicine. 2014 Mar 29. pii: S1549-9634(14)00132-4.