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AAVanced™ AAV Technology

Isolation and Shuttle Vectors

Robust AAV production

  • AAVanced Concentration Reagent
  • Isolate rAAV directly from media
  • No cell lysates or centrifugation
  • Saves time and cost-effective
  • Compatible with all serotypes

AAV Technology

Adeno-associated virus (AAV) is a single-strand DNA virus belonging to the Parvoviridae family. AAV can infect a wide range of cell types, including both dividing and quiescent cells. In humans, AAV infection is not associated with any known diseases, thus it has been widely adopted for delivery of recombinant DNA for in vivo applications. Recombinant adeno-associated virus (rAAV) vectors have been developed via removal of the AAV packaging signal from the virus genome. While the native virus integrates into a specific genomic locus in the host cell (AAVS1, located in chromosome 19q13.13), rAAV vectors persist in an extrachromosomal state with a very low frequency of random integration. Therefore, rAAV vectors have been broadly used in gene therapy and genome engineering as an alternative to other viral gene delivery methods.

AAVanced™ Concentration Reagent

One-step rAAV particle isolation from packaging cell media

AAVanced™ Cloning and Expression Vectors

Collection of cDNA cloning and expression vectors with multiple promoter and marker formats