| CELL
TYPE |
TD FACTOR |
CATALOG# |
REFERENCE |
| iPSC |
Oct4 |
TD1002PA-1 |
Takahashi, K., K. Tanabe, et al. (2007). "Induction of
pluripotent stem cells from adult human fibroblasts by defined factors."
Cell 131(5):
861-72. |
| Sox2 |
TD1003PA-1 |
|
| c-Myc |
TD1007PA-1 |
|
| Klf4 |
TD1006PA-1 |
|
| Lin28 |
TD1004PA-1 |
Yu, J., M. A. Vodyanik, et al. (2007).
"Induced pluripotent stem cell lines derived from human somatic
cells." Science
318(5858): 1917-20. |
| Nanog |
TD1005PA-1 |
| |
|
|
| Mir-302bcad/367 |
TDH101PA-G |
Anokye-Danso, F., C. M. Trivedi, et al. (2011)."Highly
efficient miRNA-mediated reprogramming of mouse and human somatic cells to
pluripotency." Cell Stem Cell 8(4): 376-88. |
| |
|
|
| Mir-302 |
TD1010PA-1 (made to order) |
Miyoshi, N., H. Ishii, et al. (2011). "Reprogramming of
mouse and human cells to pluripotency using mature microRNAs." Cell Stem Cell 8(6):
633-8. |
| Mir-200c |
TD1020PA-1 |
|
| Mir-369 |
TD1030PA-1 |
|
| |
|
|
|
| Cardiomyocyte |
Tbx5 |
TD1101PA-1 |
Ieda,
M., J. D. Fu, et al. (2010). "Direct reprogramming of fibroblasts into
functional cardiomyocytes by defined factors." Cell 142(3): 375-86. |
| Mef2c |
TD1102PA-1 |
| Gata-4 |
TD1103PA-1 |
| Mesp1 |
TD1104PA-1 |
| |
|
|
| Mir-1-1 |
TD1120PA-1 |
Ivey, K. N., A. Muth, et al. (2008). "MicroRNA regulation
of cell lineages in mouse and human embryonic stem cells." Cell Stem Cell 2(3):
219-29. |
| |
|
|
| Oct4 |
TD1002PA-1 |
Efe,
J. A., S. Hilcove, et al. (2011). "Conversion of mouse fibroblasts into
cardiomyocytes using a direct reprogramming strategy." Nat Cell Biol 13(3):
215-22. |
| Sox2 |
TD1003PA-1 |
| Klf4 |
TD1006PA-1 |
| C-Myc |
TD1007PA-1 |
| |
|
|
|
| Neuron |
Brn2 |
TD1201PA-1 |
Vierbuchen,
T., et al. (2010). "Direct
conversion of fibroblasts to functional neurons by defined factors." Nature 463(7284):
1035-41. |
| Ascl1 |
TD1202PA-1 |
| Mytl1 |
TD1203PA |
| Zic1 |
TD1204PA-1 |
| |
|
|
| Brn2 |
TD1201PA-1 |
Pang,
Z. P., et al. (2011). "Induction
of human neuronal cells by defined transcription factors." Nature 476(7359):
220-3. |
| Ascl1 |
TD1202PA-1 |
| Mytl1 |
TD1203PA |
| NeuroD1 |
TD1206PA-1 |
| |
|
|
| Mir-9 |
TD1220PA-1 |
Yoo,
A. S., et al. (2011).
"MicroRNA-mediated conversion of human fibroblasts to
neurons." Nature
476(7359): 228-31. |
| Mir-124 |
TD1221PA-1 |
| Ascl1 |
TD1202PA-1 |
| Mytl1 |
TD1203PA |
| |
|
|
| Ascl1 |
TD1202PA-1 |
Caiazzo,
M.et al. (2011). "Direct generation of functional dopaminergic neurons
from mouse and human fibroblasts." Nature 476(7359): 224-7. |
| Brn2 |
TD1201PA-1 |
| Mytl1 |
TD1203PA-1 |
| Lmx1a |
TD1208PA-1 |
| FoxA2 |
TD1304PA-1 |
| |
|
|
| Mytl1 |
TD1203PA-1 |
Ambasudhan,
R., M. Talantova, et al. (2011). "Direct Reprogramming of Adult Human
Fibroblasts to Functional Neurons under Defined Conditions." Cell Stem Cell 9(2):
113-8. |
| Brn2 |
TD1201PA-1 |
| Mir-124 |
TD1221PA-1 |
| |
|
|
| Oct4 |
TD1002PA-1 |
Kim,
J., J. A. Efe, et al. (2011). "Direct reprogramming of mouse fibroblasts
to neural progenitors." Proc Natl Acad Sci. 108(19): 7838-43. |
| Sox2 |
TD1003PA-1 |
| Klf4 |
TD1006PA-1 |
| C-Myc |
TD1007PA-1 |
| |
|
|
|
| Dopaminergic Neurons |
Ascl1 |
TD1202PA-1 |
Pfisterer,
U., A. Kirkeby, et al. (2011).
"Direct conversion of human fibroblasts to dopaminergic
neurons." Proc Natl Acad Sci.108(25):10343-8. |
| Brn2 |
TD1201PA-1 |
| Mytl1 |
TD1203PA-1 |
| Foxa2 |
TD1304PA-1 |
| Lmx1a |
TD1208PA-1 (made to order) |
| |
|
|
|
| Motor Neurons |
Lhx3 |
TD1212PA-1 (made to order) |
Son,
E. Y., J. K. Ichida, et al. (2011).
"Conversion of Mouse and Human Fibroblasts into Functional Spinal
Motor Neurons." Cell Stem Cell. |
| Ascl1 |
TD1202PA-1 |
| Brn2 |
TD1201PA-1 |
| Mytl1 |
TD1203PA-1 |
| Ngn2 |
TD1209PA-1 (made to order) |
| Hb9 |
TD1210PA-1 (made to order) |
| Isl1 |
TD1211PA-1 (made to order) |
| NeuroD1 |
TD1206PA-1 |
| |
|
|
|
| Hepatocytes |
Gata-4 |
TD1103PA-1 |
Huang,
P., Z. He, et al. (2011). "Induction of functional hepatocyte-like cells
from mouse fibroblasts by defined factors." Nature 475(7356): 386-9. |
| HNF1-alpha |
TD1306PA-1 (made to order) |
| Foxa3 |
TD1305PA-1 (made to order) |
| |
|
|
| HNF4-alpha |
TD1307PA-1 (made to order) |
Sekiya,
S. and A. Suzuki (2011). "Direct conversion of mouse fibroblasts to
hepatocyte-like cells by defined factors." Nature
475(7356): 390-3. |
| Foxa1 |
TD1303PA-1 |
| Foxa2 |
TD1304PA-1 |
| Foxa3 |
TD1305PA-1 |
| |
|
|
|
| Beta-Cell |
Ngn3 |
TD1501PA-1 |
Zhou,
Q., J. Brown, et al. (2008). "In vivo reprogramming of adult pancreatic
exocrine cells to beta-cells." Nature 455(7213): 627-32. |
| Pdx1 |
TD1502PA-1 |
| MafA |
TD1503PA-1 (made to order) |
| VP16 |
TD1504PA-1 (made to order) |
| |
|
|
|
| Blood Progenitor |
Oct4 |
TD1002PA-1 |
Szabo,
E., S. Rampalli, et al. "Direct conversion of human fibroblasts to
multilineage blood progenitors." Nature 468(7323): 521-6 |
| Gata1 |
TD1401PA-1 |
| Gata2 |
TD1402PA-1 |
| Gata3 |
TD1403PA-1 |
| Gata-4 |
TD1103PA-1 |
| |
|
|
|
| Myocytes |
MyoD |
TD1601PA-1 |
Davis, R. L., H. Weintraub, et al. (1987). "Expression of a
single transfected cDNA converts fibroblasts to myoblasts." Cell 51(6): 987-1000. |
| |
|
|
| Mir-1-1 |
TD1120PA-1 |
Cordes,
K. R., N. T. Sheehy, et al. (2009). "miR-145 and miR-143 regulate smooth
muscle cell fate and plasticity." Nature 460(7256): 705-10. |
| Mir-133 |
TD1620PA-1 |
| Mir-143 |
TD1621PA-1 |
| Mir-145 |
TD1622PA-1 |
| |
|
|
|
| Osteoblast |
Mir-2861 |
TD1820PA-1 |
Ivey, K. N. and D. Srivastava (2011). "MicroRNAs as
regulators of differentiation and cell fate decisions." Cell Stem Cell 7(1):
36-41. |
| |
|
|
|
| Osteoclast |
C-fos |
TD1900PA-1 |
|
| Mitf |
TD1901PA-1 |
| Tfe3 |
TD1902PA-1 |
| |
|
|
|
| Endothelium |
Runx1 |
TD1701PA-1 |
|
| C-Myb |
TD1702PA-1 |
|
|
|
|
