Monitor stem cells during differentiaion Choose from Five Categories: Neural, Hematopoietic, Myogenic, Structural and Signaling
All Stem Cell Differentiation Reporters are available as lentivector plasmids or as pre-packaged lentiviral preparations (using the HIV lentiviral backbone and pseudotyped with VSV-G protein)—ready for transduction of target cells. The standard product size is 10 ug of plasmid or 1 x 10^6 IFUs per packaged lentiviral reporter. Positive and negative transduction control plasmids and pre-packaged viral particles are also available.
Monitor Stem Cell Differentiation in Real-time Ravin R, Hoeppner DJ, Munno DM, Carmel L, Sullivan J, Levitt DL, Miller JL, Athaide C, Panchision DM, McKay RD. Potency and fate specification in CNS stem cell populations in vitro. Cell Stem Cell. 2008 Dec 4;3(6):670-80.
Live imaging of neuronal differentiation
Final live-cell photo of mGFAP reporter for Astrocytes
Simultaneously Track Multiple Lineages from iPS and Progenitor Cells
Additional Differentiation Reporter Data
Hematopoietic Differentiation Reporters Target Cell type
Species
Promoter/
Enhancer
Element
Official name
Other Names
Packaged Virus Catalog #
Reporter plasmid Catalog #
B-cell
Human
B29
CD79B
CD79b, Ig-beta, Igb, Igbeta
SR1004VA-1
SR1004PA-1
B-cell
Mouse
B29
Cd79b
Cd79b
SR1005VA-1
SR1005PA-1
CD8 T-cell
Mouse
CD8
Cd8a
BB154331, Ly-2, Ly-35, Ly-B, Lyt-2
SR1006VA-1
SR1006PA-1
Erythroid
Human
HLA-DRa
HLA-DRA
HLA-DRA1, major histocompatibility complex, class II, DR alpha
SR1007VA-1
SR1007PA-1
Macrophage, microglia
Mouse
Cd68
Cd68
macrosialin, Scard1, gp110
SR1008VA-1
SR1008PA-1
Pan T-cell
Human
CD2
CD2
SRBC, T11
SR1009VA-1
SR1009PA-1
Lymphocyte
Human
LCK
YT16, p56lck, pp58lck
SR10032VA-1
SR10032PA-1
Myogenic Differentiation Reporters Target Cell type
Species
Promoter/
Enhancer
Element
Official name
Other Names
Packaged Virus Catalog #
Reporter plasmid Catalog #
Cardiomyocyte
Mouse
Actc
Actc1
cardiac muscle alpha actin 1
SR10010VA-1
SR10010PA-1
Cardiomyocyte
Human
MLC-2v
MYL2
MYL2, MLC2
SR10011VA-1
SR10011PA-1
Cardiomyocyte
Human
TNNT2
TNNT2
troponin T type 2 (cardiac), TnTC, cTnT
SR10012VA-1
SR10012PA-1
Cardiomyocyte
Mouse
Tnnt2
Tnnt2
Tnt, cTnT
SR10013VA-1
SR10013PA-1
Smooth muscle myocyte
Mouse
SM22a
Tagln
Transgelin (Tagln), SM22, Sm22a
SR10014VA-1
SR10014PA-1
Cardiomyocyte
Human
ACTC
ACTC, CMD1R
SR10049VA-1
SR10049PA-1
Skeletal myocyte
Mouse
Myogenin
myo; MYF4
SR10050VA-1
SR10050PA-1
Neural Differentiation Reporters Target Cell type
Species
Promoter/
Enhancer
Element
Official name
Other Names
Packaged Virus Catalog #
Reporter plasmid Catalog #
Macrophage, microglia
Mouse
Cd68
Cd68
macrosialin, Scard1, gp110
SR1008VA-1
SR1008PA-1
Astrocyte
Human
GFAP
GFAP
Glial fibrillary acidic protein
SR10015VA-1
SR10015PA-1
Astrocyte
Mouse
Gfap
Gfap
Glial fibrillary acidic protein
SR10016VA-1
SR10016PA-1
Microglia
Human
CD11b
ITGAM
integrin, alpha M, CD11B, CR3A, MAC-1, MAC1A, MGC117044, MO1A
SR10017VA-1
SR10017PA-1
Microglia
Mouse
EMR1
Emr1
EGF-like module containing, mucin-like, hormone receptor-like sequence 1, EGF-TM7, F4/80
SR10018VA-1
SR10018PA-1
Microglia
Mouse
Iba-1
Aif1
allograft inflammatory factor 1 (Aif-1), ionized calcium binding adapter molecule 1 (Iba-1)
SR10019VA-1
SR10019PA-1
Muller glia
Mouse
Cd44
Cd44
HERMES, Ly-24, Pgp-1
SR10020VA-1
SR10020PA-1
Neuron
Human
BM88
Cend1
cell cycle exit and neuronal differentiation 1 (Cend1)
SR10021VA-1
SR10021PA-1
Neuron
Mouse
Camk2a
Camk2a
CaMK II; alpha-CaMKII
SR10022VA-1
SR10022PA-1
Neuron
Mouse
GAD67
Gad1
glutamic acid decarboxylase 1, EP10, GAD67, Gad-1
SR10023VA-1
SR10023PA-1
Neuron
Rat
NSE
Eno2
enolase 2, gamma (Eno2), neuron-specific enolase (NSE)
SR10024VA-1
SR10024PA-1
Neuron
Mouse
Ta1 a-tubulin
Tuba1a
tubulin, alpha 1A (Tuba1a), Tuba-1, Tuba1
SR10025VA-1
SR10025PA-1
Oligodendrocyte
Mouse
MBP
Mbp
myelin basic protein (Mbp), myelin deficient; shiverer
SR10026VA-1
SR10026PA-1
Photoreceptor
Human
Opsin
OPN1SW
opsin 1 (cone pigments), short-wave-sensitive (color blindness, tritan)
SR10027VA-1
SR10027PA-1
Neural Stem Cell
Rat
Nestin
Nes
SR10034VA-1
SR10034PA-1
Neural Stem Cell
Human
Nestin
NES
SR10035VA-1
SR10035PA-1
Neuron
Human
Doublecortin
DBCN, DC, LISX, SCLH, XLIS
SR10041VA-1
SR10041PA-1
Neuron
Human
MAP2
MAP2A, MAP2B, MAP2C
SR10047VA-1
SR10047PA-1
Neuron
Human
FABP7
B-FABP, BLBP, DKFZp547J2313, FABPB, MRG
SR10048VA-1
SR10048PA-1
Structural Differentiation Reporters Target Cell type
Species
Promoter/
Enhancer
Element
Official name
Other Names
Packaged Virus Catalog #
Reporter plasmid Catalog #
Chondrocyte
Mouse
Col2a1
Col2a1
collagen, type II, alpha 1
SR1001VA-1
SR1001PA-1
Osteoblast
Human
SPP1
SPP1
secreted phosphoprotein 1 (SPP1), osteopontin (OPN)
SR1002VA-1
SR1002PA-1
Osteoblast
Human
Osteocalcin
BGLAP
bone gamma-carboxyglutamate (BGLAP), BGP, PMF1
SR1003VA-1
SR1003PA-1
Adipocyte
Mouse
ALBP
422/aP2, ALBP/Ap2, Ap2, Lbpl
SR10036VA-1
SR10036PA-1
Epithelium
Human
Keratin 14
CK14, EBS3, EBS4, K14, NFJ
SR10038VA-1
SR10038PA-1
Signaling Differentiation Reporters
Target Cell type
Species
Promoter/
Enhancer
Element
Official name
Other Names
Packaged Virus Catalog #
Reporter plasmid Catalog #
Beta cell
Human
Insulin
INS
insulin
SR10028VA-1
SR10028PA-1
Islet
Human
NGN3
neurogenin 3, Atoh5, Math4B, bHLHa7, neurog3
SR10037VA-1
SR10037PA-1
Islet
Human
PDX 1
IDX-1, IPF1, IUF1, MODY4, PDX-1, STF-1
SR10039VA-1
SR10039PA-1
Islet
Mouse
Pdx1
IDX-1, IPF-1, Ipf1, Mody4, STF-1, pdx-1
SR10040VA-1
SR10040PA-1
Tumor Human p21,
Cip 1
p21 Cyclin-dependent kinase inhibitor 1A (p21, Cip1)
SR10101VA-1 SR10101PA-1 Tumor Human CDH1 CDH1 Cadherin 1, type 1, E-cadherin (epithelial) SR10102VA-1 SR10102PA-1
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