Product Citations
Gumireddy K, Li A, Gimotty PA, Klein-Szanto AJ, Showe LC, Katsaros D, Coukos G, Zhang L, Huang Q. KLF17 is a negative regulator of epithelial-mesenchymal transition and metastasis in breast cancer. Nat Cell Biol. 2009 Oct 4. [Epub ahead of print]. (PDF) »
Xu M, Takanashi M, Oikawa K, Tanaka M, Nishi H, Isaka K, Kudo M, Kuroda M. USP15 plays an essential role for caspase-3 activation during Paclitaxel-induced apoptosis. Biochem Biophys Res Commun. 2009 Oct 16;388(2):366-71. (PDF) »
Chen Y, Cairns R, Papandreou I, Koong A, Denko NC. Oxygen consumption can regulate the growth of tumors, a new perspective on the warburg effect. PLoS One. 2009 Sep 15;4(9):e7033. (PDF) »
Yeung ML, Houzet L, Yedavalli VS, Jeang KT. A genome-wide short hairpin RNA (shRNA) screening of Jurkat T-cells for human proteins contributory to productive HIV-1 replication. J Biol Chem. 2009 May 20. [Epub ahead of print]. (PDF) »
Ossovskaya VS, Dolganov G, Basbaum AI. Loss of function genetic screens reveal MTGR1 as an intracellular repressor of beta1 integrin-dependent neurite outgrowth. J Neurosci Methods. 2009 Mar 15;177(2):322-33. (PDF) »
Huang X, Wang JY, Lu X. Systems analysis of quantitative shRNA-library screens identifies regulators of cell adhesion. BMC Syst Biol. 2008 Jun 13;2:49. (PDF) »
Hwang GW, Hayashi T, Kita K, Takahashi T, Kuge S, Naganuma A. siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells. J Toxicol Sci. 2007 Dec;32(5):581-3. (PDF) »
Hattori H, Zhang X, Jia Y, Subramanian KK, Jo H, Loison F, Newburger PE,Luo HR. RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells. Blood, 110 (2): 640-650, 2007 (PDF) »
How to use shRNA libraries for genetic screening
Nature. 2004 Mar 25;428(6981):427-31
Nature. 2004 Mar 25;428(6981):431-7
Proc Natl Acad Sci U S A. 2004 Jan 6;101(1):135-40
Vu N. Ngo, R. Eric Davis, Laurence Lamy, Xin Yu, Hong Zhao, Georg Lenz, Lloyd T. Lam, Sandeep Dave, Liming Yang, John Powell & Louis M. Staudt. A loss-of-function RNA interference screen for molecular targets in cancer. Nature. 2006 May 4;441(7089):106-10. (PDF) »
siRNA Library Review
Jason Moffat and David M. Sabatini. Building mammalian signalling pathways with RNAi screens. Nat Rev Mol Cell Biol. 2006 Mar;7(3):177-87. (PDF) »
Pooled siRNA libraries
Guryanova O. A., Makhanov M., Chenchik A. A., Chumakov P. M., and Frolova E. I. Optimization of a genome-wide disordered lentivector-based short hairpin RNA library. Molecular Biology 40 (3): 448-459, 2006. (PDF) »
Hattori H, Zhang X, Jia Y, Subramanian KK, Jo H, Loison F, Newburger PE, Luo HR. RNAi screen identifies UBE2D3 as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells. Blood, 110 (2): 640-650, 2007. (PDF) »
Devi G. R. siRNA-based approaches in cancer therapy. Cancer Gene Therapy 13: 819-829, 2006.
