Product citations
shRNA Cloning and Expression Lentivectors:
Chong HC, Tan MJ, Philippe V, Tan SH, Tan CK, Ku CW, Goh YY, Wahli W, Michalik L, Tan NS. Regulation of epithelial-mesenchymal IL-1 signaling by PPARbeta/delta is essential for skin homeostasis and wound healing. J Cell Biol. 2009 Mar 23;184(6):817-31. (PDF) »
Basu HS, Thompson TA, Church DR, Clower CC, Mehraein-Ghomi F, Amlong CA, Martin CT, Woster PM, Lindstrom MJ, Wilding G. A small molecule polyamine oxidase inhibitor blocks androgen-induced oxidative stress and delays prostate cancer progression in the transgenic adenocarcinoma of the mouse prostate model. Cancer Res. 2009 Oct 1;69(19):7689-95. (PDF) »
Mehraein-Ghomi F, Lee E, Church DR, Thompson TA, Basu HS, Wilding G. JunD mediates androgen-induced oxidative stress in androgen dependent LNCaP human prostate cancer cells. Prostate. 2008 Jun 15;68(9):924-34. (PDF) »
Maruyama R., Aoki F., Toyota M., Sasaki Y., Akashi H., Mita H., Suzuki H., Akino K., Ohe-Toyota M., Maruyama Y., Tatsumi H., Imai K., Shinomura Y., and Tokino T.
Comparative Genome Analysis Identifies the Vitamin D Receptor Gene as a Direct Target of p53-Mediated Transcriptional Activation. Cancer Research 66 (9): 4574-4583, 2006. Lai Y. C., Shaftel S. S., Miller J. H., Tallents R. H., Chang Y., Pinkert C. A., Olschowka J. A., Dickerson I. M., Puzas J. E., O’Banion M. K., and Krykanides S. Intraarticular Induction of Interleukin-1 Expression in the Adult Mouse, With Resultant Temporomandibular Joint Pathologic Changes, Dysfunction, and Pain. ARTHRITIS & RHEUMATISM 54 (4): 1184-1197, 2006.
Shaftel S. S., Kyrkanides S., Olschowka J. A., Miller J. H., Johnson R. E., and O’Banion M. K. Sustained hippocampal IL-1ß overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology. J. Clin. Invest. 117:1595-1604, 2007.
Brueggemann L. I., Moran C. J., Barakat J. A., Yeh J. Z., Cribbs L. L., and Byron K. L. Vasopressin Stimulates Action Potential Firing by Protein Kinase C-dependent Inhibition of KCNQ5 in A7R5 Rat Aortic Smooth Muscle Cells. Am J Physiol Heart Circ Physiol (October 27, 2006). doi:10.1152/ajpheart.00065.2006.
Van Maerken T., Speleman F., Vermeulen J., Lambertz I., De Clercq, S., De Smet E., Yigit N., Coppens, V., Philippe J., De Paepe A., Marine J.-C., and Vandesompele J. Small-Molecule MDM2 Antagonists as a New Therapy Concept for Neuroblastoma. Cancer Research 66: 9646-9655, 2006.
Journal of Biomolecular Screening, 11 (8): 1059-1068, 2006.
Geng D., Joshi S. K., Podolsky R., and She J.-X., GCSF receptor regulates antigen uptake and expression of cytokines and costimulatory molecules in dendritic cells. Molecular Immunology, 44 (4): 521-529, 2007.
Si Z., Vandegraaff N., O”hUigin C., Song B., Yuan W., Xu C., Perron M., Li X., Marasco W. A., Engelman A., Dean M. and Sodroski J. Evolution of a cytoplasmic tripartite motif (TRIM) protein in cows that restricts retroviral infection. PNAS, 103 (19): 7454-7459, 2006.
Li W., Hardwick M., Rpsenthal D., Culty M., and Papadopoulos V. Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation. Biochemical Pharmacology 73 (4): 491-503, 2007.
cDNA Cloning and Expression Lentivectors:
Schroen B., Leenders J. J., van Erk A., AT Bertrand A. T., van Loon M., van Leeuwen R. E., Kubben N., Duisters R. F., Schellings M. W., Janssen B. J., Debets J. J., Schwake M., Hoydal M. A., Heymans S., Saftig P., and Pinto Y. M. Lysosomal integral membrane protein 2 is a novel component of the cardiac intercalated disc and vital for load-induced cardiac myocyte hypertrophy. Journal of Experimental Medicine 204 (5): 1227-1235, 2007.
Schlaepfer D. D., Hou S., Lim S. T., Tomar A., Yu H., Lim Y., Hanson D. A., Uryu S. A., Molina J., and Mitra S. K. Tumor Necrosis Factor-(alpha) Stimulates Focal Adhension Kinase Required for Mitogen-activated Kinase-associated Interleukin 6 Expression. J. Biol. Chem. 282 (24): 17450-17459, 2007.
Parikh H., Carlsson E., Chutkow W. A., Johansson L. E., Storgaard H., Poulsen P., Saxena R., Ladd C., Schulze P. C., Mazzini M. J., Jensen C. B., Krook A., Björnholm M., Tornqvist H., Zierath J. R., Ridderstråle M., Altshuler D., Lee R. T. , Vaag A.,1,2 Groop L. C., and Mootha V. K. TXNIP Regulates Peripheral Glucose Metabolism in Humans. Plos Med. 4 (5): e158, 2007.
Eddy E., Cohen W., Lingen M. W., Zhu B., Zhu H., Straza M. W., Pierce C., Martin L. E., and Rosner M. R. Protein Kinase C (zeta) Mediates Epidermal Growth Factor–Induced Growth of Head and Neck Tumor Cells by Regulating Mitogen-Activated Protein Kinase. Cancer Research 66: 6296-6303, 2006.
Patwari P., Higgins L. J., Chutkow W. A., Yoshioka J., Lee R. T. The Interaction of thioredoxin with Txnip: EVIDENCE FOR FORMATION OF A MIXED DISULFIDE BY DISULFIDE EXCHANGE. J. Biol. Chem. 281 (31): 21884-21891, 2006.
Stoner M. A., Auerbach S. S., Zamule S. M., Strom S. C., and Omiecinski C. Transactivation of a DR-1 PPRE by a human constitutive androstane receptor variant expressed from internal protein translation start sites. Nucleic Acids Research 35 (7): 2177-2190, 2007.
Transcriptional Reporters:
Christina H. Stuelten, Anil K. Kamaraju, Lalage M.Wakefield and Anita B. Roberts. Lentiviral reporter constructs for fluorescence tracking of the temporospatial pattern of Smad3 signaling. BioTechniques 43:289-294 (September 2007). (PDF) »
Ebauer M., Wachtel M., Niggli F. K., Schäfer B. W. Comparative expression profiling identifies an invi target gene signature with TFAP2B as a mediator of the survival function of PAX3/FKHR. Oncogene Advance Online Publication May 21, 2007; doi: 10.1038/sj.onc.1210525.
pPACK Lentivector Packaging System:
Liu B, Peng XC, Zheng XL, Wang J, Qin YW. MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo. Lung Cancer. 2009 Feb 13. [Epub ahead of print].
Thal D, Xavier CP, Rosentreter A, Linder S, Friedrichs B, Waha A, Pietsch T, Stumpf M, Noegel A, Clemen C. Expression of coronin-3 (coronin-1C) in diffuse gliomas is related to malignancy. J Pathol. 2008 Mar;214(4):415-24.
Li W., Hardwick M., Rpsenthal D., Culty M., and Papadopoulos V. Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation. Biochemical Pharmacology 73 (4): 491-503, 2007.
Sarojini H., Medepalli K., Terry D. A., Alphenaar B. W., and Wang E. Localized delivery of DNA to the cells by viral collagen-loaded silica colloidal crystals. BioTechniques® 43(2): Advanced Online Publication, 2007.
Stoner M. A., Auerbach S. S., Zamule S. M., Strom S. C., and Omiecinski C. J. Transactivation of a DR-1 PPRE by a human constitutive androstane receptor variant expressed from internal protein translation start sites. Nucleic Acids Research 35 (7): 2177-2190, 2007.
Solomon S. Shaftel, Stephanos Kyrkanides, John A. Olschowka, Jen-nie H. Miller, Renee E. Johnson and M. Kerry O’Banion. Sustained hippocampal IL-1ß overexpression mediates chronic neuroinflammation and ameliorates Alzheimer plaque pathology. J. Clin. Invest., 117:1595-1604, 2007.
Lee J.-J., Chen P. B., Yang S.-H., Cheng C.-H., Chueh L.-L., Pang V. F., Michael Hsiao M., Lin C.-T. Effect of the VP3 gene of chicken anemia virus on canine mammary tumor cell. American Journal of Veterinary Research 68 (4): 411-422, 2007.
Journal of Biomolecular Screening, 11(8): 1059-1068, 2006.
Lentivirus Producer Cell Line:
Liu B, Peng XC, Zheng XL, Wang J, Qin YW. MiR-126 restoration down-regulate VEGF and inhibit the growth of lung cancer cell lines in vitro and in vivo. Lung Cancer. 2009 Feb 13. [Epub ahead of print].
Zhang Q, Huang A, Lin YC, Yu HG. Associated changes in HCN2 and HCN4 transcripts and I(f) pacemaker current in myocytes. Biochim Biophys Acta. 2009 Feb 21.
Liu J., Guan X., Ma X. Regulation of IL-27 p28 gene expression in macrophages through MyD88-and interferon- (gamma)-mediated Pathways. Journal of Experimental Medicine, 204 (1): 141-152, 2007.
Peng X, Zhang X, Zeng B. Locally administered lentivirus-mediated siRNA inhibits wear debris-induced inflammation in murine air pouch model. Biotechnol Lett. 2008 Nov;30(11):1923-9.
PEG-It Lentivirus Concentration Solution:
Pintchovski SA, Peebles CL, Kim HJ, Verdin E, Finkbeiner S. The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons. J Neurosci. 2009 Feb 4;29(5):1525-37.
Zhang Q, Huang A, Lin YC, Yu HG. Associated changes in HCN2 and HCN4 transcripts and I(f) pacemaker current in myocytes. Biochim Biophys Acta. 2009 Feb 21.
Badri KR, Zhou Y, Dhru U, Aramgam S, Schuger L. Effects of the SANT domain of tension-induced/inhibited proteins (TIPs), novel partners of the histone acetyltransferase p300, on p300 activity and TIP-6-induced adipogenesis. Mol Cell Biol. 2008 Oct;28(20):6358-72.
Interferon-response Detection Kit:
Samakoglu S., Lisowski L., Budak-Alpdogan T., Usachenko Y., Acuto S.., Di Marzo R., Maggio A., Zhu P.., Tisdale J. F., Riviere I., and Sadelain M. A genetic strategy to treat sickle cell anemia by coregulating globin transgene expression and RNA Interference. Nature Biotechnology 24(1): 89-94, 2006.
Xiang S., Fruehauf J., and Li C. J. Short hairpin RNA-expressing bacteria elicit RNA interference in mammals. Nature Biotechnology 24 (6): 697-701, 2006.
Ong S. T., Li F., Du J., Tan Y., Wang S. Hybrid Cytomegalovirus Enhancer-H1 Promoter Based Plasmid and Baculovirus Vectors Mediate Effective RNA Interference. Human Gene Therapy 16 (12): 1404-1412, 2005.
Review:
Constans A. RNAi: Five Tips to Better Silencing. The Scientist, June 2006.
