miRZips anti-microRNAs
Permanent microRNA suppression
Permanent microRNA interference
- Lentiviral-based anti-sense microRNAs
- Use both GFP and Puro selection
- Dissect microRNA regulated pathways
miRZips™ Lentiviral-based MicroRNA Inhibition
Features and Benefits
- Stable & permanent anti-microRNA expression from constitutive H1 promoter
- Rationally designed, asymmetric hairpins optimized for anti-sense microRNA production
- miRZip anti-sense microRNAs efficiently suppress specific endogenous microRNAs
- Reliable delivery to dividing or non-dividing cells
- Select for positive expressing cells with either GFP or Puro selection
- Uncover phenotypes using powerful anti-microRNA interference
- Pool of prepackaged viral particles containing the entire anti-microRNA collection for high-throughput phenotypic screens also available
