Modulation of miR-29a Target Protein levels using SBI's Lenti-miR-29a and miRZip-29a microRNA constructs

U937 Human leukemic monocyte lymphoma cell lines were transduced with control lentivirus (Control), Lenti-miR-29a (Overexpress) or miRZip-29a (Knockdown). The overexpression of miR-29a downregulated Target Protein levels and the suppression of endogenous miR-29a with miRZip-29a significantly de-repressed (upregulated) Target Protein levels.

Western Blot analysis of Target Protein levels

The higher the levels of microRNA-29a, the lower the levels of Target Protein and vice versa.

• List of miRZip clones