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Ruebel K, Leontovich AA, Stilling GA, Zhang S, Righi A, Jin L and Lloyd RV. MicroRNA expression in ileal carcinoid tumors: downregulation of microRNA-133a with tumor progression. Mod Pathol. 1-9. 2009 Dec 25. (PDF) »
Ng EK, Chong WW, Jin H, Lam EK, Shin VY, Yu J, Poon TC, Ng SS, Sung JJ. (2009). Differential expression of microRNAs in plasma of colorectal cancer patients: A potential marker for colorectal cancer screening. Gut. 2009 Feb 9. (PDF) »
Xian Wang, Emily K.Y. Lam, Jianbin Zhang, Hongchuan Jin, Joseph J.Y. Sung. MicroRNA-122a functions as a novel tumor suppressor downstream of adenomatous polyposis coli in gastrointestinal cancers. Biochemical and Biophysical Research Communications 387 (2009) 376–380.
Ng EK, Tsang WP, Ng SS, Jin HC, Yu J, Li JJ, Röcken C, Ebert MP, Kwok TT, Sung JJ MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancer. Br J Cancer. 2009 Jul 28. [Epub ahead of print]
Zhang Y, Li M, Wang H, Fisher WE, Lin PH, Yao Q, Chen C. Profiling of 95 MicroRNAs in Pancreatic Cancer Cell Lines and Surgical Specimens by Real-Time PCR Analysis. World J Surg. 2008 Nov 22.
Changyi Chen, Hong Chai, Xinwen Wang, Jun Jiang, Md Saha Jamaluddin, Dan Liao, Yuqing Zhang, Hao Wang, Uddalak Bharadwaj, Sheng Zhang, Min Li, Peter Lin, and Qizhi Yao. Soluble CD40 ligand induces endothelial dysfunction in human and porcine coronary artery endothelial cells. Blood, 15 October 2008, Vol. 112, No. 8, pp. 3205-3216.
AACR 2008 QuantiMir Technology Highlights
Click for AACR 2008 QuantiMir Technology Highlights "Aryl hydrocarbon receptor agonists inhibit breast cancer cell growth and modulate microRNA expression. Zhang, et al."
MicroRNA and Cancer References
Breast Cancer:
MicroRNA gene expression deregulation in human breast cancer. Cancer Res. 2005 Aug 15;65(16):7065-70. Iorio MV, Ferracin M, Liu CG, Veronese A, Spizzo R, Sabbioni S, Magri E, Pedriali M, Fabbri M, Campiglio M, Menard S, Palazzo JP, Rosenberg A, Musiani P, Volinia S, Nenci I, Calin GA, Querzoli P, Negrini M, Croce CM.
MicroRNA expression profiles classify human cancers. Lu J, Getz G, Miska EA, Alvarez-Saavedra E, Lamb J, Peck D, Sweet-Cordero A, Ebert BL, Mak RH, Ferrando AA, Downing JR, Jacks T, Horvitz HR, Golub TR.
B-cell Leukemia:
MicroRNA profiling reveals distinct signatures in B cell chronic lymphocytic leukemias. Proc Natl Acad Sci U S A. 2004 Aug 10;101(32):11755-60. Epub 2004 Jul 29. Calin GA, Liu CG, Sevignani C, Ferracin M, Felli N, Dumitru CD, Shimizu M, Cimmino A, Zupo S, Dono M, Dell'Aquila ML, Alder H, Rassenti L, Kipps TJ, Bullrich F, Negrini M, Croce CM.
A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia. N Engl J Med. 2005 Oct 27;353(17):1793-801. Calin GA, Ferracin M, Cimmino A, Di Leva G, Shimizu M, Wojcik SE, Iorio MV, Visone R, Sever NI, Fabbri M, Iuliano R, Palumbo T, Pichiorri F, Roldo C, Garzon R, Sevignani C, Rassenti L, Alder H, Volinia S, Liu CG, Kipps TJ, Negrini M, Croce CM.
Lung Cancer:
Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell. 2006 Mar;9(3):189-98. Yanaihara N, Caplen N, Bowman E, Seike M, Kumamoto K, Yi M, Stephens RM, Okamoto A, Yokota J, Tanaka T, Calin GA, Liu CG, Croce CM, Harris CC.
A polycistronic microRNA cluster, miR-17-92, is overexpressed in human lung cancers and enhances cell proliferation. Cancer Res. 2005 Nov 1;65(21):9628-32. Hayashita Y, Osada H, Tatematsu Y, Yamada H, Yanagisawa K, Tomida S, Yatabe Y, Kawahara K, Sekido Y, Takahashi T.
MicroRNA and lung cancer N Engl J Med. 2005 Jun 9;352(23):2446-8. Eder M, Scherr M.
Pancreatic Cancer:
Expression profiling identifies microRNA signature in pancreatic cancer. Int J Cancer. 2006 Dec 5; [Epub ahead of print] Lee EJ, Gusev Y, Jiang J, Nuovo GJ, Lerner MR, Frankel WL, Morgan DL, Postier RG, Brackett DJ, Schmittgen TD.
Solid Tumors:
A microRNA expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2257-61. Epub 2006 Feb 3. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, Prueitt RL, Yanaihara N, Lanza G, Scarpa A, Vecchione A, Negrini M, Harris CC, Croce CM.
MicroRNA and Cancer Reviews/Other Publications:
Cancer genomics: small RNAs with big impacts. Nature. 2005 Jun 9;435(7043):745-6. Meltzer, PS. MicroRNAs in Gene Regulation: When the Smallest Governs It All. J Biomed Biotechnol. 2006;2006(4):69616. Ouellet DL, Perron MP, Gobeil LA, Plante P, Provost P.
MicroRNAs as oncogenes. Curr Opin Genet Dev. 2006 Feb;16(1):4-9. Epub 2005 Dec 19. Hammond SM.
Oncomirs - microRNAs with a role in cancer. Nat Rev Cancer. 2006 Apr;6(4):259-69. Esquela-Kerscher A, Slack FJ.
microRNAs as oncogenes and tumor suppressors. Dev Biol. 2006 Aug 16; [Epub ahead of print] Zhang B, Pan X, Cobb GP, Anderson TA.
MicroRNAs and the hallmarks of cancer. Oncogene. 2006 Oct 9;25(46):6170-5. Dalmay T, Edwards DR
microRNAs exhibit high frequency genomic alterations in human cancer. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):9136-41. Epub 2006 Jun 5. Zhang L, Huang J, Yang N, Greshock J, Megraw MS, Giannakakis A, Liang S, Naylor TL, Barchetti A, Ward MR, Yao G, Medina A, O'brien-Jenkins A, Katsaros D, Hatzigeorgiou A, Gimotty PA, Weber BL, Coukos G.