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SparQ™ Cumate Switch

Ultimate control technology for inducible
cDNA or microRNA expression in mammalian cells

Cumate Inducible Lentivectors

  • Zero background leakiness
  • Robust induction
  • Dynamic titratability
  • Turn on->off->on again

Fine tune the induction by adding more cumate

Choose your induction level
Cumate is non-toxic to cells and allows for greater dynamic ranges of induction levels. Increasing amounts of cumate added offers a linear induction of expression.

 

Increase induction levels by adding more SparQ lentivirus
The cumate switch also supports titration of expression through increasing amounts of transducing SparQ cumate switch lentivirus constructs. The switch responds even with 30 MOI of cumate switch virus.