SparQ™ Cumate Switch
Ultimate control technology for inducible
cDNA or microRNA expression in mammalian cells
Cumate Inducible Lentivectors
- Zero background leakiness
- Robust induction
- Dynamic titratability
- Turn on->off->on again
Online Resources
Technical References
Mullick A, Xu Y, Warren R, Koutroumanis M, Guilbault C, Broussau S, Malenfant F, Bourget L, Lamoureux L, Lo R, Caron AW, Pilotte A, Massie B. The cumate gene-switch: a system for regulated expression in mammalian cells. BMC Biotechnol. 2006 Nov 3;6:43.
Gaillet B, Gilbert R, Broussau S, Pilotte A, Malenfant F, Mullick A, Garnier A, Massie B. High-level recombinant protein production in CHO cells using lentiviral vectors and the cumate gene-switch. Biotechnol Bioeng. 2010 Jun 1;106(2):203-15.
Broussau S, Jabbour N, Lachapelle G, Durocher Y, Tom R, Transfiguracion J, Gilbert R, Massie B. Inducible packaging cells for large-scale production of lentiviral vectors in serum-free suspension culture. Mol Ther. 2008 Mar;16(3):500-7.